Latest Research in Natural Antidiabetic Agents Studies

Top Research Topics in Natural Antidiabetic Agents Studies

• Natural Antidiabetic Agents Studies — 11 papers
• Synthesis and biological activity — 6 papers
• Histone Deacetylase Inhibitors Research — 3 papers
• Angiogenesis and VEGF in Cancer — 3 papers
• HER2/EGFR in Cancer Research — 3 papers
• Cancer therapeutics and mechanisms — 2 papers
• Enzyme function and inhibition — 2 papers
• Multicomponent Synthesis of Heterocycles — 2 papers
• PARP inhibition in cancer therapy — 1 papers
• Bacteriophages and microbial interactions — 1 papers

Highest-Cited Papers

1. Simultaneous Inhibition of PARP-1 and CK2α by Novel Benzothieno[3,2- d ]pyrimidin-4(1 H )-one Derivatives: A Promising Strategy to Combat Homologous Recombination Deficiency-Independent Tumors and Metastasis
2. Integrated AI-Driven Multi-Objective Optimization of Sulfamoylbenzamide-Based HBV Capsid Assembly Modulators: Discovery of 11B-6 with Superior Potency and Drug-like Properties
3. Design, synthesis, and computational assessment of bis ‑oxadiazole ligands targeting α-amylase and α-glucosidase: DFT, docking, and ADME studies
4. Discovery of Tetrasubstituted Quinazolin-4(3 H )-ones as Wild-type-sparing, Highly Selective PI3KαH1047R Inhibitors
5. Synthesis, in vitro enzyme inhibitory and antioxidant activities of novel S -Alkylated indole-1,2,4-triazole acyl hydrazones targeting type 2 diabetes
6. Targeting the Zinc Metalloproteinase Superfamily in the CNS: Medicinal Chemistry Strategies To Optimize Selectivity, Pharmacokinetics, and Blood–Brain Barrier Permeability
7. Structure-Based Drug Design of Quinoline CYP8B1 Inhibitors for the Potential Treatment of Metabolic Disease
8. Quantum Theoretical, Chemo-Computational, and Comparative Molecular Coupling Studies of Two Enantiomeric Naphthoquinones, Alkannin and Shikonin, and Their Corresponding Indole Derivatives
9. Design and in silico screening of novel isoniazid-based Schiff base derivatives followed by synthesis and biological evaluation of the lead compound against Mycobacterium tuberculosis H37Rv
10. AN OVERVIEW OF CURRENT RESEARCH ON THE DEVELOPMENT OF ANTHRAQUINONES AS ANTICANCER AGENTS
11. Exploring benzofuran derivatives as selective MAO-B inhibitors: a multilayered in silico study
12. Structure-Guided Development of Selective HDAC4 and HDAC7 Inhibitors That Modulate Th17 Cell Transcription
13. Aurone Derivatives as Inhibitors of ERK Phosphorylation in HCC827 Non-Small Cell Lung Cancer Cells
14. Exploring the antidiabetic potential of DHA-salicylaldehyde-chalcone endowed 1,2,3-triazole hybrids: synthesis, α-glucosidase inhibition and molecular modeling studies
15. Design, Synthesis, In Vitro Biological Evaluation, and In Silico Studies of Novel Imidazo[4,5‐ b ]Pyridine‐Acrylonitrile‐Based Derivatives as VEGFR‐2 Inhibitors Against Breast Cancer and Hepatocellular Carcinoma
16. 1,3,4-Oxadiazole derivatives as potential anti-glioma agents: synthesis, characterization, in vitro cytotoxic activity against HS683 cells, and molecular docking
17. In Silico Design and Green Synthesis of Polyhydroxy Conjugated Piperidine and Pyrrolidine Derivatives for In vitro Antiglycation Activity
18. Coumarin derivatives combating antibacterial resistance: molecular modeling-driven insights and comprehensive SAR elucidation targeting DNA gyrase and topoisomerase IV
19. Investigation of 1H-1,2,3-triazole derivatives as TGF-β pathway targeted therapeutics for oral squamous cell carcinoma: an in-silico approach
20. A fungal-derived benzothiazole derivative overcomes osimertinib resistance in NSCLC by targeting SCD1