Latest Research in Bioinformatics and Genomic Networks

Top Research Topics in Bioinformatics and Genomic Networks

• Single-cell and spatial transcriptomics — 13 papers
• Bioinformatics and Genomic Networks — 4 papers
• Epigenetics and DNA Methylation — 4 papers
• Genomics and Chromatin Dynamics — 4 papers
• AI in cancer detection — 3 papers
• Methodology — 3 papers
• Telomeres, Telomerase, and Senescence — 2 papers
• Cell Image Analysis Techniques — 2 papers
• DNA Repair Mechanisms — 2 papers
• Ubiquitin and proteasome pathways — 2 papers

Highest-Cited Papers

1. STcompare: comparative spatial transcriptomics data analysis of structurally matched tissues to characterize differentially spatially patterned genes (2 citations)
2. Hex -MASP for mapping the whole-tissue spatial proteome and the intrabrain distribution of monoclonal antibodies (1 citations)
3. Computational multi-omics integration in neurocognitive disorders from machine learning to graph-based approaches
4. The DNMT1 CXXC domain senses CpG islands for DNA methylation inhibition
5. ConvexGating infers gating strategies from clusters in single cell cytometry data
6. Cell-type-specific surfaceome profiling of 100-500 isolated cells using a droplet-based Magnetic Affinity Purification System
7. Mammalian DNA maintenance methylation depends on histone but not PAF15 ubiquitination
8. Charting critical transient gene interactions in disease progression across bulk, single-cell, and spatial transcriptomics
9. Segmentation of placental tissue using immunofluorescent staining and an artificial intelligence-based analysis workflow
10. A robust, scalable K-statistic for quantifying immune cell clustering in spatial proteomics data
11. Reproducibility-driven clinical translation of spatial multi-omics in precision medicine
12. Ten quick tips for spatial transcriptomics analysis
13. Machine learning-supported identification of necrosis in colorectal and pancreatic cancer spheroids
14. Poly(ADP-ribose) mediates TRPS1 phase transition
15. Beyond End Protection: Shelterin, POT1 Dysfunction, and Telomere Replication Stress in Cancer
16. A Framework for Quantifying DNA Methylation Heterogeneity and Detecting Co-methylated loci from Native Nanopore Sequencing
17. Spatialgater: an R Shiny webtool for in situ gating of cells in spatial omics experiments
18. Insights Into Spatial Transcriptomics: Exploring Recent Technical Developments and Their Diverse Applications
19. Modelling missing modalities in multi-omics clinical outcome prediction
20. Analysis of multicellular anatomical structures from spatial omics data using sosta