Latest Research in Molecular Dynamics and Transcriptomics

Top Research Topics in Molecular Dynamics and Transcriptomics

• Single-cell and spatial transcriptomics — 102 papers
• Genomics and Chromatin Dynamics — 48 papers
• Extracellular vesicles in disease — 46 papers
• Microtubule and mitosis dynamics — 38 papers
• Cellular Mechanics and Interactions — 31 papers
• DNA Repair Mechanisms — 29 papers
• Protein Degradation and Inhibitors — 26 papers
• RNA Research and Splicing — 24 papers
• Machine Learning — 24 papers
• interferon and immune responses — 23 papers

Highest-Cited Papers

1. The Tri-Layer Genetic Code The Fundamental Equation of Biological Information - DNA (5 citations)
2. Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation (4 citations)
3. Cohesin prevents local mixing of condensed euchromatic domains in living human cells (7 citations)
4. Modulation of the cytoskeleton for cancer therapy (8 citations)
5. End processing in NHEJ by Polymerase λ and PNKP is coordinated during short-range synapsis (3 citations)
6. Submolecular video-imaging of the Smc5/6 complex topologically bound to DNA (2 citations)
7. On the use of variational autoencoders for biomedical data integration (1 citations)
8. Beyond benchmarking: an expert-guided consensus approach to spatially aware clustering (3 citations)
9. STcompare: comparative spatial transcriptomics data analysis of structurally matched tissues to characterize differentially spatially patterned genes (2 citations)
10. Photocatalytic proximity labeling for the identification of G-quadruplex DNA-interacting proteins (3 citations)
11. Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing (2 citations)
12. The human cytomegalovirus vGPCR UL33 is essential for efficient lytic replication in epithelial cells (2 citations)
13. Molecular basis of nick ligation in the nucleosome by DNA Ligase IIIα (2 citations)
14. Reconstitution of multistep recruitment of ULK1 to membranes in autophagy (1 citations)
15. Conformational asymmetry of replicated human chromosomes (3 citations)
16. TM184C is a GPCR-like regulator of intercellular exchange and autophagy (1 citations)
17. SMURF2 inhibits autophagic control of Mycobacterium tuberculosis in macrophages (1 citations)
18. Live dynamics of induced cell-cell fusion between mitotic and interphasic cells (2 citations)
19. SPEF1 mediates assembly of central pair microtubule complexes in cilia of Tetrahymena (1 citations)
20. Truthful visualizations for mass spectrometry imaging enable high-spatial-resolution interactive m/z mapping and exploration (2 citations)

Sub-Regions

• Spatial Transcriptomics and Cell Atlas — 254 papers
• Microbial Genetic Systems — 225 papers
• Genomic Regulatory Networks — 158 papers
• CRISPR-Mediated Proteostasis and Gene Engineering — 155 papers
• Host Immune and Viral Defense — 149 papers
• Antibody Engineering and Pathogen Interaction — 108 papers
• Cellular Mechanics and Chromatin Dynamics — 91 papers
• Prostate Oncology and Immunotherapy — 64 papers