Latest Research in Genomic Regulatory Networks

Top Research Topics in Genomic Regulatory Networks

• Single-cell and spatial transcriptomics — 30 papers
• Genomics and Chromatin Dynamics — 18 papers
• Machine Learning — 12 papers
• DNA Repair Mechanisms — 11 papers
• RNA Research and Splicing — 7 papers
• Bioinformatics and Genomic Networks — 5 papers
• Gene Regulatory Network Analysis — 5 papers
• RNA modifications and cancer — 3 papers
• Methodology — 3 papers
• Epigenetics and DNA Methylation — 3 papers

Highest-Cited Papers

1. Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation (4 citations)
2. Cohesin prevents local mixing of condensed euchromatic domains in living human cells (7 citations)
3. End processing in NHEJ by Polymerase λ and PNKP is coordinated during short-range synapsis (3 citations)
4. On the use of variational autoencoders for biomedical data integration (1 citations)
5. Photocatalytic proximity labeling for the identification of G-quadruplex DNA-interacting proteins (3 citations)
6. Unraveling single-molecule reactions via multiplexed in-situ DNA sequencing (2 citations)
7. Conformational asymmetry of replicated human chromosomes (3 citations)
8. scProtoTransformer: Scalable reference mapping across molecules, cells, and donors (1 citations)
9. The KH-like CTD of Prp5 is conserved and essential for splicing
10. BEAR-GRN: Systematic assessment of single-cell multi-omics-based gene regulatory network inference methods
11. Genome-Wide Detection of DNA Lesions at Single-Base Resolution Using Glycosylase-Cleavage Ligation-Assisted Sequencing
12. Learning chemical-induced gene expression perturbations with WAVE
13. When models choose metrics: Hidden geometry in computational biology
14. A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics
15. Regulatory-prior-guided attention preserves biological structure during unpaired single-cell RNA–ATAC integration
16. N4BP1 uses tandem KH domains to associate with EDC4 and mRNA decapping factors in P-bodies
17. The PAXT connection is a modifier of rare codon-enriched protein expression
18. Ashwin and FAM98 paralogs define nuclear and cytoplasmic RNA ligase complexes for tRNA biogenesis
19. Dynamic Generalized Gromov-Wasserstein Optimal Transport
20. CellRFT: Reinforcement Fine-Tuning for Single-Cell Perturbation Modeling

Sub-Regions

• Machine Learning — 49 papers
• Protein Degradation and Inhibitors — 31 papers
• Single-cell and spatial transcriptomics — 22 papers
• Advanced Electron Microscopy Techniques and Applications — 21 papers
• DNA Repair Mechanisms — 19 papers
• Cell Image Analysis Techniques — 17 papers