Latest Research in CRISPR-Mediated Proteostasis and Gene Engineering

Top Research Topics in CRISPR-Mediated Proteostasis and Gene Engineering

• Protein Degradation and Inhibitors — 24 papers
• CRISPR and Genetic Engineering — 22 papers
• RNA modifications and cancer — 10 papers
• Genomics and Chromatin Dynamics — 7 papers
• interferon and immune responses — 5 papers
• RNA Interference and Gene Delivery — 4 papers
• Machine Learning — 4 papers
• RNA Research and Splicing — 4 papers
• Genomics and Phylogenetic Studies — 4 papers
• Ubiquitin and proteasome pathways — 4 papers

Highest-Cited Papers

1. The Tri-Layer Genetic Code The Fundamental Equation of Biological Information - DNA (5 citations)
2. Molecular basis of nick ligation in the nucleosome by DNA Ligase IIIα (2 citations)
3. Stoichiometry-Dependent Specificity in Biotin Enrichment: A Benchmarking Framework for Proximity-Labeling Proteomics (1 citations)
4. Accurately modeling RNase H-mediated antisense oligonucleotide efficacy. (1 citations)
5. The Architect of Life: CRISPR and the Future
6. Regulatory roles of G-quadruplexes and G-quadruplex-binding proteins across the enhancer and promoter of the HBV genome
7. Integrative mapping of chloroplast rRNA modifications reveals conserved and lineage-specific features and stepwise modification during plastid ribosome biogenesis
8. The Architect of Life: CRISPR and the Future
9. Non-Destructive Chemoselective Labeling and Bioorthogonal Enrichment of Pseudouridine-Containing RNA via Facile N 1-Selective Functionalization
10. Production of MarathonRT and its comparison with commercial reverse transcriptases for tRNA sequencing library preparation
11. Ubiquitin receptor–mediated, ubiquitin-independent targeted protein degradation via 26 S proteasomes
12. Resolution of viral R-loop by DHX9 promotes hepatitis B virus replication
13. Precision Genome Engineering in Human Disease: Expanding Therapeutic Roles of CRISPR Technologies.
14. A 16-bp deletion in the first intron of Eda is not responsible for the loss of lateral plates in threespine stickleback
15. MoDPA: Inferring Modification-dependent Protein Associations from Uniformly Reprocessed Mass Spectrometry
16. Hsc70-Mediated Targeting Chimeras for Targeted Protein Degradation via Chaperone-Mediated Autophagy
17. MonoXtract: A Deep Learning Framework for Extracting Transmembrane Protein Dynamics from Single-Color Single-Molecule Imaging
18. Functional characterization of viral transcriptional regulators reveals extensive rewiring of host pathways
19. Structural framework for the assembly of the human tRNA ligase complex
20. Recurrent reversible mutations at gaf1 driving metastable TORC1 inhibitor resistance in fission yeast

Sub-Regions

• RNA Interference and Gene Delivery — 34 papers
• Protein Degradation and Inhibitors — 33 papers
• Genomics and Chromatin Dynamics — 31 papers
• Genomics and Phylogenetic Studies — 31 papers
• CRISPR and Genetic Engineering — 29 papers
• DNA and Nucleic Acid Chemistry — 22 papers