Latest Research in CRISPR and Genetic Engineering

29 research papers · 2026 median publication year

Top Research Topics in CRISPR and Genetic Engineering

Highest-Cited Papers

  1. Ubiquitin receptor–mediated, ubiquitin-independent targeted protein degradation via 26 S proteasomes
  2. Resolution of viral R-loop by DHX9 promotes hepatitis B virus replication
  3. Hsc70-Mediated Targeting Chimeras for Targeted Protein Degradation via Chaperone-Mediated Autophagy
  4. Cyclosporin A triggers a RIG-I-mediated interferon response through multiple cellular processes
  5. Coronavirus Nsp5‑mediated dual‑site cleavage of GSDMA modifies its antiviral and proinflammatory functions
  6. Detection and sequencing of Ap 2 N-capped RNAs in human cells
  7. Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
  8. Leveraging high-throughput proteomics and AI-based protein folding to accelerate VAV1 molecular glue discovery
  9. Rewriting the cancer epigenome: CRISPR technologies for DNA methylation editing
  10. Structural Signatures of the O6-Methylguanine Lesion: A Multi-Method Feature Selection Analysis of Molecular Dynamics Simulations
  11. Polyamines as emerging regulators of RNA biology: linking the epitranscriptome, translation, hypusination and post-transcriptional gene regulation
  12. MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts
  13. Minimal CBX3-Derived UCOE Confers Long-Term Resistance to Transgene Silencing in Human iPSCs During Neuronal Differentiation
  14. EGFR-Degrading PROTACs and Calcium Peroxide Co-loaded Liposomes: Enabling EGFR Degradation and Hypoxia Alleviation as Dual Safeguards for NSCLC Therapy.
  15. A Single-Administration AAV Gene Therapy Expressing an Affinity-Detuned Feline AIM (m-fAIM) for Chronic Kidney Disease in the Domestic Cat: A Theoretical Development Program
  16. A Single-Administration AAV Gene Therapy Expressing an Affinity-Detuned Feline AIM (m-fAIM) for Chronic Kidney Disease in the Domestic Cat: A Theoretical Development Program
  17. Thermodynamic and Statistical Signatures of Modality Changes in Concentration Distributions Driven by Stochastic Switching Between Two Activity States
  18. Transient Expression of an IL-1Ra−Fc Fusion Cytokine in Tobacco Species for Improved Anti-inflammatory Therapeutic Potential
  19. Modulation of Host Cell Death Signaling Platforms by Plasmodium falciparum: Implications for Eryptosis Regulation and Parasite Survival
  20. The inspiration of CRISPR-Cas: Interface of nature with a pharmacy: A compatible horizon of cancer treatment
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L3 Region - - 2026 Sep Q3

CRISPR and Genetic Engineering

29 papers

Top Topics (10)

CRISPR and Genetic Engineering6
Protein Degradation and Inhibitors5
interferon and immune responses2
RNA modifications and cancer2
Virus-based gene therapy research2
Hepatitis B Virus Studies1
Inflammasome and immune disorders1
DNA Repair Mechanisms1
Polyamine Metabolism and Applications1
Pluripotent Stem Cells Research1

Top Publications (20)

1.Ubiquitin receptor–mediated, ubiquitin-independent targeted protein degradation via 26 S proteasomes2.Resolution of viral R-loop by DHX9 promotes hepatitis B virus replication3.Hsc70-Mediated Targeting Chimeras for Targeted Protein Degradation via Chaperone-Mediated Autophagy4.Cyclosporin A triggers a RIG-I-mediated interferon response through multiple cellular processes5.Coronavirus Nsp5‑mediated dual‑site cleavage of GSDMA modifies its antiviral and proinflammatory functions6.Detection and sequencing of Ap 2 N-capped RNAs in human cells7.Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation8.Leveraging high-throughput proteomics and AI-based protein folding to accelerate VAV1 molecular glue discovery9.Rewriting the cancer epigenome: CRISPR technologies for DNA methylation editing10.Structural Signatures of the O6-Methylguanine Lesion: A Multi-Method Feature Selection Analysis of Molecular Dynamics Simulations11.Polyamines as emerging regulators of RNA biology: linking the epitranscriptome, translation, hypusination and post-transcriptional gene regulation12.MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts13.Minimal CBX3-Derived UCOE Confers Long-Term Resistance to Transgene Silencing in Human iPSCs During Neuronal Differentiation14.EGFR-Degrading PROTACs and Calcium Peroxide Co-loaded Liposomes: Enabling EGFR Degradation and Hypoxia Alleviation as Dual Safeguards for NSCLC Therapy.15.A Single-Administration AAV Gene Therapy Expressing an Affinity-Detuned Feline AIM (m-fAIM) for Chronic Kidney Disease in the Domestic Cat: A Theoretical Development Program16.A Single-Administration AAV Gene Therapy Expressing an Affinity-Detuned Feline AIM (m-fAIM) for Chronic Kidney Disease in the Domestic Cat: A Theoretical Development Program17.Thermodynamic and Statistical Signatures of Modality Changes in Concentration Distributions Driven by Stochastic Switching Between Two Activity States18.Transient Expression of an IL-1Ra−Fc Fusion Cytokine in Tobacco Species for Improved Anti-inflammatory Therapeutic Potential19.Modulation of Host Cell Death Signaling Platforms by Plasmodium falciparum: Implications for Eryptosis Regulation and Parasite Survival20.The inspiration of CRISPR-Cas: Interface of nature with a pharmacy: A compatible horizon of cancer treatment
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