Latest Research in Cellular Signaling Architecture

Top Research Topics in Cellular Signaling Architecture

• Microtubule and mitosis dynamics — 18 papers
• Fungal and yeast genetics research — 9 papers
• Advanced Proteomics Techniques and Applications — 7 papers
• Genomics and Chromatin Dynamics — 6 papers
• Receptor Mechanisms and Signaling — 5 papers
• Bioinformatics and Genomic Networks — 4 papers
• Ion channel regulation and function — 4 papers
• Lipid Membrane Structure and Behavior — 4 papers
• Biological Physics — 4 papers
• Mitochondrial Function and Pathology — 4 papers

Highest-Cited Papers

1. Submolecular video-imaging of the Smc5/6 complex topologically bound to DNA (2 citations)
2. Truthful visualizations for mass spectrometry imaging enable high-spatial-resolution interactive m/z mapping and exploration (2 citations)
3. Directed evolution of Lantern enables rapid RNA and protein proximity labeling (1 citations)
4. An enantioselective covalent inhibitor of BAX confers cytoprotection in vivo (1 citations)
5. Leveraging Structure-Based Design to Overcome Class III RTK Off-Target Activity in the Development of Selective Wild-Type KIT Inhibitors (1 citations)
6. An integrated landscape of mRNA and protein isoforms (2 citations)
7. Steric control of signaling bias in the immunometabolic receptor GPR84 (1 citations)
8. The intracellular subdomain of the volume-regulated anion channel subunit LRRC8A is a hotspot of channel activation (1 citations)
9. Research Progress on Small-Molecule Inhibitors Targeting Salt-Induced Kinases
10. Cryo-EM structure of ex vivo Sup35 yeast prion and the factors defining prion phenotype
11. Direct microhaplotype genotyping for GT-seq (Genotyping-in-Thousands by Sequencing) using a diploid abundance model
12. Uncoupling of the allosteric signalling network in the β1-adrenergic receptor by a negative allosteric modulator
13. XL-MS and De Novo Protein Design Identified a Common Motif for TREM2 Binding
14. Advances in Proteomic Sample Preparation Strategies for Human Disease Biomarker Discovery
15. Integrative AI-assisted modeling suggests CPPF binding at a composite α/β-tubulin interface pocket dominated by β-tubulin contacts
16. A Robust DIA-Based Platform for Large-Scale Plasma Glycoproteomics and Biomarker Discovery
17. Imperfect Simulator Interventions: AI for Science
18. paraORA: GPU-Accelerated Exact Over-Representation Analysis for Repeated Queries of Large Gene-Set Libraries
19. Protocol for assessing protein expression levels and localization during fission yeast cytokinesis
20. A conserved tyrosine motif encodes a structural vulnerability controlling stability and activity across J-domain proteins

Sub-Regions

• Microtubule and mitosis dynamics — 27 papers
• Computation and Language — 24 papers
• Advanced Proteomics Techniques and Applications — 18 papers
• Fungal and yeast genetics research — 18 papers
• FOXO transcription factor regulation — 11 papers
• Bayesian Modeling and Causal Inference — 6 papers