Latest Research in Molecular Structure Engineering

Top Research Topics in Molecular Structure Engineering

• RNA and protein synthesis mechanisms — 45 papers
• Protein Structure and Dynamics — 41 papers
• CRISPR and Genetic Engineering — 34 papers
• Bacteriophages and microbial interactions — 26 papers
• Monoclonal and Polyclonal Antibodies Research — 25 papers
• Computational Drug Discovery Methods — 25 papers
• Machine Learning in Bioinformatics — 22 papers
• DNA and Nucleic Acid Chemistry — 22 papers
• Bacterial Genetics and Biotechnology — 22 papers
• Advanced Proteomics Techniques and Applications — 21 papers

Highest-Cited Papers

1. MemBrain v2: an end-to-end tool for the analysis of membranes in cryo-electron tomography (178 citations)
2. Lenacapavir allosterically remodels the HIV-1 capsid (7 citations)
3. ntSynt-viz: Visualizing synteny patterns across multiple genomes (21 citations)
4. In extracto cryo-EM reveals eEF2 as a major hibernation factor on 60S and 80S particles (4 citations)
5. Design of peptides with non-canonical amino acids using flow matching (6 citations)
6. Deciphering the comprehensive relationship between 5′ UTR and 3′ UTR sequences with deep learning (2 citations)
7. De novo design of RNA pseudoknots with deep learning (2 citations)
8. Improving RNA Secondary Structure Prediction Through Expanded Training Data (2 citations)
9. Functional mapping and engineering of the Sec translocon unlocked by a cell-free system (2 citations)
10. Non-standard proteins in the lens of AlphaFold 3: a case study of amyloids (12 citations)
11. The fitness landscape of a form II rubisco in a photosynthetic bacterium guides engineering of oxygen tolerance (2 citations)
12. Molecular-level observation of the self-assembly of a virus-like particle (1 citations)
13. VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formation (2 citations)
14. Septin architecture dictates size-dependent diffusion barriers on biomimetic membranes (2 citations)
15. Porcine epidemic diarrhea virus infection promotes Peyer’s patch immune induction and epithelial defense via single-cell transcriptional reprogramming (2 citations)
16. Gaugefixer: overcoming parameter non-identifiability in models of sequence-function relationships (1 citations)
17. 16S ribosomal RNA modification drives transcript-specific translation efficiency (1 citations)
18. Transposon end recognition and excision mechanisms of type I-F CRISPR-associated transposases (1 citations)
19. Spanning-tree thermostatistics of protein allostery: An exact Kirchhoff framework with application to oncogenic KRAS (1 citations)
20. Leveraging Structure-Based Design to Overcome Class III RTK Off-Target Activity in the Development of Selective Wild-Type KIT Inhibitors (1 citations)

Sub-Regions

• Genomic Regulatory Networks — 170 papers
• Cellular Signaling Architecture — 170 papers
• Protein Folding Dynamics — 74 papers
• Nucleic Acid Synthesis Mechanisms — 67 papers
• Amyloid Structural Modeling — 59 papers
• Conformational Sampling Algorithms — 31 papers
• Ligand Binding Energetics — 31 papers
• Metalloprotein Structure Engineering — 26 papers