Latest Research in Amyloid Structural Modeling

Top Research Topics in Amyloid Structural Modeling

• Protein Structure and Dynamics — 5 papers
• Melanoma and MAPK Pathways — 3 papers
• Advanced Proteomics Techniques and Applications — 3 papers
• Lipid Membrane Structure and Behavior — 3 papers
• Bioinformatics and Genomic Networks — 3 papers
• Computational Drug Discovery Methods — 2 papers
• Alzheimer's disease research and treatments — 2 papers
• Receptor Mechanisms and Signaling — 2 papers
• Genomics and Rare Diseases — 2 papers
• Quantitative Methods — 2 papers

Highest-Cited Papers

1. Non-standard proteins in the lens of AlphaFold 3: a case study of amyloids (12 citations)
2. The physicochemical design, structure and permeability of the JCVI-syn3A minimal cell membrane (1 citations)
3. Ancestral Sequences Cannot be Accurately Reconstructed via Interpolation in a Variational Autoencoder’s Latent Space
4. Fragment-Based Covalent Targeting of Lysines at the Allosteric Latch Site of SHP2
5. Conformational Landscape of a Marginally Disordered Protein HYPK and its Charge-Variant Mutant in the Context of Folded Domains
6. A Structural Perspective on Non-covalent Targeting of Conserved Polar Residues in Protein Kinases
7. Impact of Inhibitor Size and Flexibility on the Binding Pathways to c-Src Kinase
8. The Scope Concept: Defined Chemical Space for Identifying Ligand-Efficient, Tractable Hits Applied to Drug Discovery Targets Trypanosomal CLK1, 14–3–3/Estrogen Receptor-α, and SARS-CoV-2 Mpro
9. MetaproDB: A Flexible and Reproducible Framework for Biome-Informed Protein Sequence Database Construction for Metaproteomics
10. scBalFlow: A Staged Flow Matching Framework for Imbalanced Single-Cell Drug Perturbation Prediction
11. Residue-Resolved Mapping of Heterogeneous Structural Organization during Native-to-Amyloid Transition of an Amyloidogenic Protein
12. BrIS: Visualizing Internal Standards at the MS1 Level via Bromine Fingerprint for Sensitive and Robust Proteomics Quality Control
13. Thinking Outside the Binding Site: A Self‐Encapsulating Kinase Inhibitor Remodels Its Pocket to Achieve Selectivity
14. Affordability Alone Is Not the Constraint: Evolutionary Accessibility and the No-Waiting Region in GPCR-Class Signalling
15. Affordability Alone Is Not the Constraint: Evolutionary Accessibility and the No-Waiting Region in GPCR-Class Signalling
16. Statistical Theory of Lipid Membrane Conductivity and Stability Regulated by Membrane-Deforming Inclusions and External Fields
17. DeepMutate-3D: interactive protein language model mutation scanning on predicted structures
18. DeepMutate-3D: interactive protein language model mutation scanning on predicted structures
19. Reducing cost of fluorescent microscopy through dye exclusion, distillation techniques, and deep learning
20. Are You Learning Biological Signal or Shortcuts? Auditing and Mitigating Bias in Protein-Protein Interaction Datasets

Sub-Regions

• Advanced Proteomics Techniques and Applications — 14 papers
• Protein Structure and Dynamics — 13 papers
• Lipid Membrane Structure and Behavior — 9 papers
• Protein Tyrosine Phosphatases — 9 papers
• Prion Diseases and Protein Misfolding — 8 papers
• Prion Diseases and Protein Misfolding — 1 papers