Latest Research in Cancer Metabolism and Signaling

Top Research Topics in Cancer Metabolism and Signaling

• Cancer, Hypoxia, and Metabolism — 81 papers
• Ferroptosis and cancer prognosis — 64 papers
• CAR-T cell therapy research — 47 papers
• RNA modifications and cancer — 44 papers
• Extracellular vesicles in disease — 41 papers
• Immune cells in cancer — 41 papers
• Single-cell and spatial transcriptomics — 34 papers
• Immune Cell Function and Interaction — 31 papers
• interferon and immune responses — 25 papers
• Cancer, Lipids, and Metabolism — 24 papers

Highest-Cited Papers

1. Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance (5 citations)
2. Immune checkpoint molecules as biomarkers of Staphylococcus aureus bone infection and clinical outcome (2 citations)
3. cGAS-deficient mice display premature aging associated with derepression of LINE1 elements and inflammation (12 citations)
4. All-optical multimodal mapping of single-cell-type-specific metabolic activities via REDCAT (6 citations)
5. Antibody Fc receptor CD16a mediates natural killer cell activation via mechanotransduction of piconewton forces (2 citations)
6. AMPK γ-Subunit Isoform Switching Governs Temozolomide Resistance and Survival in Glioblastoma (2 citations)
7. MRI Proton Density Fat Fraction as a Biomarker of Marrow Recovery Following Organ‐Sparing Total Marrow Irradiation in Sickle Cell Disease (1 citations)
8. Mechanosensitive phosphorylation of NFATC4 at S213/S217 drives fibroblast-to-myofibroblast transition and fibrosis (1 citations)
9. Integrated signatures define mutational processes in prostate cancer (1 citations)
10. FAβ-gal: an automated fluorescence-based quantification of the senescence-associated beta-galactosidase X-gal assay (1 citations)
11. Blood flow coordinates collective endothelial cell migration during vascular plexus formation and promotes angiogenic sprout regression via vegfr3/flt4 (2 citations)
12. Truncated ErbB2 receptor expression lowers nucleus stiffness and increases migration of breast cancer cells (1 citations)
13. Unphosphorylated tyrosines mediate PD-1 inhibition of T cell signaling condensate formation (1 citations)
14. A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease (6 citations)
15. GW4869 Depletes Macrophages and Increases Number of Extracellular Vesicles in Murine Peritoneal Cavity Fluid (1 citations)
16. Positive selection of IgG over IgM plasma cells through BCR isotype–specific antigen presentation and signaling (1 citations)
17. Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species (1 citations)
18. Effects of 1 Gray radiation on the biophysical properties of the tibia and femur from hindlimb‐suspended rats
19. Targeting SHMT2 reverses lactate-driven CAF-mediated T-cell exclusion and sensitizes HNSCC to anti-PD-1 immunotherapy
20. A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasis

Sub-Regions

• Ferroptotic Cell Fate — 280 papers
• Lipid-Driven Immune Suppression — 181 papers
• Prostate Oncogenomics Mechanisms — 164 papers
• Transcriptional Splicing Dynamics — 131 papers
• Synthetic Receptor Engineering — 123 papers
• Non-Coding RNA Signaling — 107 papers
• Hypoxia Metabolic Adaptation — 105 papers
• Oncolytic Vector Immunotherapy — 82 papers