Latest Research in Hypoxia Metabolic Adaptation

105 research papers · 2026 median publication year

Top Research Topics in Hypoxia Metabolic Adaptation

Highest-Cited Papers

  1. Research progress on the interconnected network of mitophagy and energy metabolism in tumors
  2. The assembly of tetrameric human L‐lactate dehydrogenase is regulated by ionic strength, β‐ NADH binding, cyclic peptides, and long‐chain dicarboxylates
  3. Nano-Oncology Targeting the Lactate-MCT1/MCT4-Histone Lactylation Axis: A New Hallmark-Based Strategy Against Metastatic Cancer Progression
  4. Adaptive response to serine and glycine deprivation enhances the stemness potential of pancreatic cancer cells
  5. In vivo CRISPR screens identify the glutamine transporter SLC1A5 as a metabolic barrier to antitumor immunity
  6. A Novel Preclinical Mouse Model of Voluntary Active Stretching Suppresses Mammary Tumor Progression
  7. Epigenomic Remodeling by Lipid Metabolism: A Cross-Disease Perspective on Cancer and Brain Disorders
  8. TET2 as an epigenetic signaling hub: interactome networks, metabolic control and therapeutic vulnerabilities in hematologic malignancies
  9. Integrating UHPLC-MS and MALDI-MSI for Spatial Nucleoside Profiling in FFPE Breast Cancer: A Multimodal Molecular Pathology Framework
  10. Beyond Cys65: Redox Effector Factor-1 CRISPR-Engineered Cys93 and Cys99 Mutants Reveal Cooperative and Secondary Roles of Redox Signaling and Pancreatic Ductal Adenocarcinoma Progression
  11. Targeting Metabolic Pathways to Direct T-Cell Trafficking: Therapeutic Perspectives
  12. Quantitative in vivo flux analysis reveals tumor and host lipogenic remodeling in KRAS-driven lung cancer
  13. Erythropoietin in Tumor Immunity: Mechanistic Evidence, Clinical Cautions, and Translational Opportunities
  14. B Cells and Tumor Immunometabolism: Emerging Insights into Immune Regulation and Therapeutic Resistance
  15. KDM4B Maintains Pyruvate Dehydrogenase Complex Expression to Support Mitochondrial Metabolism and Survival in Cancer Cells
  16. Targeting Glycolytic Reprogramming in Gastric Cancer: Navigating the Translational Maze from Mechanism to Clinic
  17. Exploiting tumor amino acid metabolic heterogeneity: Biological principles and precision nanomedicine
  18. Integrated Metabolomic, Proteomic, and Phosphoproteomic Profiling Reveals Metabolic and Signaling Alterations Associated with CAMKK2 Inhibition in Gastric Cancer
  19. Targeting metabolic reprogramming in persister cancer cells: Emerging insights and therapeutic opportunities
  20. Glutamine sequestration promotes tumor growth and immune evasion through elevation of arginine methylation in hepatocellular carcinoma

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L2 Region - - 2026 Sep Q3

Hypoxia Metabolic Adaptation

105 papers

Top Topics (10)

Cancer, Hypoxia, and Metabolism38
Immune cells in cancer7
Ferroptosis and cancer prognosis7
RNA modifications and cancer4
Mitochondrial Function and Pathology3
Endoplasmic Reticulum Stress and Disease3
Amino Acid Enzymes and Metabolism2
Cancer, Lipids, and Metabolism2
Epigenetics and DNA Methylation2
Cancer Research and Treatments2

Top Publications (20)

1.Research progress on the interconnected network of mitophagy and energy metabolism in tumors2.The assembly of tetrameric human L‐lactate dehydrogenase is regulated by ionic strength, β‐ NADH binding, cyclic peptides, and long‐chain dicarboxylates3.Nano-Oncology Targeting the Lactate-MCT1/MCT4-Histone Lactylation Axis: A New Hallmark-Based Strategy Against Metastatic Cancer Progression4.Adaptive response to serine and glycine deprivation enhances the stemness potential of pancreatic cancer cells5.In vivo CRISPR screens identify the glutamine transporter SLC1A5 as a metabolic barrier to antitumor immunity6.A Novel Preclinical Mouse Model of Voluntary Active Stretching Suppresses Mammary Tumor Progression7.Epigenomic Remodeling by Lipid Metabolism: A Cross-Disease Perspective on Cancer and Brain Disorders8.TET2 as an epigenetic signaling hub: interactome networks, metabolic control and therapeutic vulnerabilities in hematologic malignancies9.Integrating UHPLC-MS and MALDI-MSI for Spatial Nucleoside Profiling in FFPE Breast Cancer: A Multimodal Molecular Pathology Framework10.Beyond Cys65: Redox Effector Factor-1 CRISPR-Engineered Cys93 and Cys99 Mutants Reveal Cooperative and Secondary Roles of Redox Signaling and Pancreatic Ductal Adenocarcinoma Progression11.Targeting Metabolic Pathways to Direct T-Cell Trafficking: Therapeutic Perspectives12.Quantitative in vivo flux analysis reveals tumor and host lipogenic remodeling in KRAS-driven lung cancer13.Erythropoietin in Tumor Immunity: Mechanistic Evidence, Clinical Cautions, and Translational Opportunities14.B Cells and Tumor Immunometabolism: Emerging Insights into Immune Regulation and Therapeutic Resistance15.KDM4B Maintains Pyruvate Dehydrogenase Complex Expression to Support Mitochondrial Metabolism and Survival in Cancer Cells16.Targeting Glycolytic Reprogramming in Gastric Cancer: Navigating the Translational Maze from Mechanism to Clinic17.Exploiting tumor amino acid metabolic heterogeneity: Biological principles and precision nanomedicine18.Integrated Metabolomic, Proteomic, and Phosphoproteomic Profiling Reveals Metabolic and Signaling Alterations Associated with CAMKK2 Inhibition in Gastric Cancer19.Targeting metabolic reprogramming in persister cancer cells: Emerging insights and therapeutic opportunities20.Glutamine sequestration promotes tumor growth and immune evasion through elevation of arginine methylation in hepatocellular carcinoma

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