Latest Research in Lipid-Driven Immune Suppression

181 research papers · 2026 median publication year

Top Research Topics in Lipid-Driven Immune Suppression

Highest-Cited Papers

  1. Spatiotemporal metabolic networks in a preclinical model of pancreatic cancer and associated cachexia
  2. Functional diversity of natural human IFNB1 variants in innate immunity
  3. Lipopolysaccharide-induced glycolytic reprogramming drives H3K18 lactylation-mediated inflammatory injury in buffalo mammary epithelial cells.
  4. Lactate-induced H3K9 lactylation disrupts the inner blood–retinal barrier by activating the PTK2–FMNL2 axis in diabetic retinopathy
  5. Histone H3K18 Lactylation Drives Immunosuppression by Upregulating CD38 in Myeloid-Derived Suppressor Cells in Lung Cancer
  6. DGKα and ζ deficiency causes regulatory T-cell dysregulation, destabilization, and conversion to pathogenic T-follicular helper cells to trigger IgG1-predominant autoimmunity
  7. Study on the potential mechanism of AIM2 regulating fatty acid synthesis and promoting cervical cancer invasion
  8. Lactate suppresses innate immunity in Caenorhabditis elegans by excessive activation of SKN-1 associated with histone H4K16 lactylation
  9. Balancing lipid synthesis and oxidation promotes B cell response to vaccination during immunosuppression
  10. Reconstructing Human Long-Term Hematopoietic Stem Cells
  11. Microfluidic Strategies for Immune Cell Enumeration and Functional Analysis Directly from Whole Blood
  12. IL-11 drives Treg cell differentiation by activating the MBD3/APOH-mediated fatty acid oxidation axis to promote hepatocellular carcinoma
  13. Sublethal heat stress-induced HSF4 upregulation via GRSF1 in an m6A-dependent manner in hepatocellular carcinoma
  14. RUNX1 links ATF4-associated stress adaptation to microenvironmental remodeling in POSTN+ fibroblasts during skin fibrosis
  15. Lysine pyruvylation: decoding the molecular language of pyruvate signaling
  16. Basophil Extracellular Traps in Immunity and Disease
  17. Temporal CRAC channel blockade modulates the MYC-MXD axis to attenuate autoimmune inflammation
  18. Serum metabolomic alterations associated with vascular invasion and early recurrence in hepatocellular carcinoma: a prospective pilot study
  19. TGF-β1 signaling in Crohn’s disease
  20. The Lactate–Lactylation Axis as a Metabolic–Epigenetic Framework for Therapeutic Adaptation in Esophageal Squamous Cell Carcinoma

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L2 Region - - 2026 Sep Q3

Lipid-Driven Immune Suppression

181 papers

Top Topics (10)

Cancer, Hypoxia, and Metabolism14
Cancer, Lipids, and Metabolism13
Immune cells in cancer8
Inflammatory Bowel Disease7
Ferroptosis and cancer prognosis7
Single-cell and spatial transcriptomics5
interferon and immune responses4
T-cell and B-cell Immunology4
RNA modifications and cancer4
Metabolomics and Mass Spectrometry Studies4

Top Publications (20)

1.Spatiotemporal metabolic networks in a preclinical model of pancreatic cancer and associated cachexia2.Functional diversity of natural human IFNB1 variants in innate immunity3.Lipopolysaccharide-induced glycolytic reprogramming drives H3K18 lactylation-mediated inflammatory injury in buffalo mammary epithelial cells.4.Lactate-induced H3K9 lactylation disrupts the inner blood–retinal barrier by activating the PTK2–FMNL2 axis in diabetic retinopathy5.Histone H3K18 Lactylation Drives Immunosuppression by Upregulating CD38 in Myeloid-Derived Suppressor Cells in Lung Cancer6.DGKα and ζ deficiency causes regulatory T-cell dysregulation, destabilization, and conversion to pathogenic T-follicular helper cells to trigger IgG1-predominant autoimmunity7.Study on the potential mechanism of AIM2 regulating fatty acid synthesis and promoting cervical cancer invasion8.Lactate suppresses innate immunity in Caenorhabditis elegans by excessive activation of SKN-1 associated with histone H4K16 lactylation9.Balancing lipid synthesis and oxidation promotes B cell response to vaccination during immunosuppression10.Reconstructing Human Long-Term Hematopoietic Stem Cells11.Microfluidic Strategies for Immune Cell Enumeration and Functional Analysis Directly from Whole Blood12.IL-11 drives Treg cell differentiation by activating the MBD3/APOH-mediated fatty acid oxidation axis to promote hepatocellular carcinoma13.Sublethal heat stress-induced HSF4 upregulation via GRSF1 in an m6A-dependent manner in hepatocellular carcinoma14.RUNX1 links ATF4-associated stress adaptation to microenvironmental remodeling in POSTN+ fibroblasts during skin fibrosis15.Lysine pyruvylation: decoding the molecular language of pyruvate signaling16.Basophil Extracellular Traps in Immunity and Disease17.Temporal CRAC channel blockade modulates the MYC-MXD axis to attenuate autoimmune inflammation18.Serum metabolomic alterations associated with vascular invasion and early recurrence in hepatocellular carcinoma: a prospective pilot study19.TGF-β1 signaling in Crohn’s disease20.The Lactate–Lactylation Axis as a Metabolic–Epigenetic Framework for Therapeutic Adaptation in Esophageal Squamous Cell Carcinoma

Sub-Regions (6)

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