Latest Research in Neuroinflammation and Neurodegeneration Mechanisms

19 research papers · 2026 median publication year

Top Research Topics in Neuroinflammation and Neurodegeneration Mechanisms

Highest-Cited Papers

  1. MDM2-linked microglial dysfunction in obsessive-compulsive disorder
  2. Integrated Single-cell and Bulk Transcriptome Analysis Characterizes a Candidate Ccl4/Lgals3/Egr1 Expression Pattern Associated with Immunometabolic Dysregulation in Traumatic Brain Injury
  3. Histone Post-Translational Modifications at the Metabolism–Chromatin Interface: Reprogramming of Neuroinflammation in Alzheimer’s Disease
  4. A Molecularly Anchored Spatial Transcriptomic Framework for Precise CA1–Subiculum Parcellation and Region-Resolved Analysis in Alzheimer’s Disease
  5. Peripheral TDP-43 pathology in amyotrophic lateral sclerosis: toward a systemic proteinopathy
  6. Single-nucleus transcriptomic analysis reveals subfield-specific cell-to-cell synaptic reorganisation of the mouse hippocampus in focal temporal lobe epilepsy
  7. Aging is associated with behavioral alterations, lysosomal dysfunction, region-specific inflammation, and glutamatergic synaptic impairments in a Grn knockout mouse model of frontotemporal dementia
  8. Microglial GRB2 is essential for brain ventriculogenesis and CSF homeostasis
  9. Spatio-Temporal Expression Patterns of Connexins 43 and 30 in Hippocampal Astrocytes During Postnatal Development
  10. FKBP5 promotes pro-inflammatory microglial activation and neuronal injury through NF-κB/NLRP3 signaling in convulsive status epilepticus
  11. Peripheral Neuroinflammatory MicroRNA Signatures and Altered Correlation Networks Associated with Pharmacoresistance in Temporal Lobe Epilepsy
  12. Toward brain-derived extracellular vesicles as biochemical biopsies of synucleinopathies
  13. Identification of Age-Associated Upstream Regulators to Promote Neuronal Resilience in HD Patient-Derived Neurons
  14. Priming of CD8+ T cells by peripheral dendritic cells exacerbates tau-mediated neurodegeneration
  15. From wild to domestic: Single-cell transcriptomic perspectives on hippocampal regulation and evolution
  16. Integrative Transcriptomic Mapping Reveals C1Q/AP-Like Microglial State Reconfiguration in Temporal Lobe Epilepsy with Hippocampal Sclerosis
  17. AKAP11 links autophagy to cognitive impairment in psychiatric diseases
  18. Core activation program and selective regional responsiveness of microglia during aging and parabiosis
  19. From a developmental atlas to maps of disease origin
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L3 Region - - 2026 Sep Q3

Neuroinflammation and Neurodegeneration Mechanisms

19 papers

Top Topics (10)

Neuroinflammation and Neurodegeneration Mechanisms4
Alzheimer's disease research and treatments2
Single-cell and spatial transcriptomics2
Amyotrophic Lateral Sclerosis Research2
Obsessive-Compulsive Spectrum Disorders1
Cerebrospinal fluid and hydrocephalus1
Connexins and lens biology1
Epilepsy research and treatment1
Parkinson's Disease Mechanisms and Treatments1
Genetic Neurodegenerative Diseases1

Top Publications (19)

1.MDM2-linked microglial dysfunction in obsessive-compulsive disorder2.Integrated Single-cell and Bulk Transcriptome Analysis Characterizes a Candidate Ccl4/Lgals3/Egr1 Expression Pattern Associated with Immunometabolic Dysregulation in Traumatic Brain Injury3.Histone Post-Translational Modifications at the Metabolism–Chromatin Interface: Reprogramming of Neuroinflammation in Alzheimer’s Disease4.A Molecularly Anchored Spatial Transcriptomic Framework for Precise CA1–Subiculum Parcellation and Region-Resolved Analysis in Alzheimer’s Disease5.Peripheral TDP-43 pathology in amyotrophic lateral sclerosis: toward a systemic proteinopathy6.Single-nucleus transcriptomic analysis reveals subfield-specific cell-to-cell synaptic reorganisation of the mouse hippocampus in focal temporal lobe epilepsy7.Aging is associated with behavioral alterations, lysosomal dysfunction, region-specific inflammation, and glutamatergic synaptic impairments in a Grn knockout mouse model of frontotemporal dementia8.Microglial GRB2 is essential for brain ventriculogenesis and CSF homeostasis9.Spatio-Temporal Expression Patterns of Connexins 43 and 30 in Hippocampal Astrocytes During Postnatal Development10.FKBP5 promotes pro-inflammatory microglial activation and neuronal injury through NF-κB/NLRP3 signaling in convulsive status epilepticus11.Peripheral Neuroinflammatory MicroRNA Signatures and Altered Correlation Networks Associated with Pharmacoresistance in Temporal Lobe Epilepsy12.Toward brain-derived extracellular vesicles as biochemical biopsies of synucleinopathies13.Identification of Age-Associated Upstream Regulators to Promote Neuronal Resilience in HD Patient-Derived Neurons14.Priming of CD8+ T cells by peripheral dendritic cells exacerbates tau-mediated neurodegeneration15.From wild to domestic: Single-cell transcriptomic perspectives on hippocampal regulation and evolution16.Integrative Transcriptomic Mapping Reveals C1Q/AP-Like Microglial State Reconfiguration in Temporal Lobe Epilepsy with Hippocampal Sclerosis17.AKAP11 links autophagy to cognitive impairment in psychiatric diseases18.Core activation program and selective regional responsiveness of microglia during aging and parabiosis19.From a developmental atlas to maps of disease origin
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