Latest Research in Transcriptomic Neuropathology Mapping

Top Research Topics in Transcriptomic Neuropathology Mapping

• Alzheimer's disease research and treatments — 16 papers
• Neuroinflammation and Neurodegeneration Mechanisms — 12 papers
• Parkinson's Disease Mechanisms and Treatments — 10 papers
• Amyotrophic Lateral Sclerosis Research — 8 papers
• Neurogenesis and neuroplasticity mechanisms — 7 papers
• Single-cell and spatial transcriptomics — 6 papers
• Extracellular vesicles in disease — 5 papers
• Neuroscience and Neuropharmacology Research — 4 papers
• Barrier Structure and Function Studies — 3 papers
• Ion channel regulation and function — 3 papers

Highest-Cited Papers

1. Single-cell transcriptomic atlas of Alzheimer's disease middle temporal gyrus reveals region, cell type, and sex specificity of gene expression with novel genetic risk for MERTK in female (22 citations)
2. Molecular characterization of tetraploid astrocytes in drug-resistant temporal lobe epilepsy
3. sTREM2 and GFAP mediated the association of cerebrospinal fluid GLP-1R with tau pathology in alzheimer’s disease
4. Human cellular models of the brain to study lipid homeostasis in Alzheimer’s disease and related dementias
5. Network-based gene prioritization using hybrid scoring for complex disease module discovery
6. Is adverse outcome in PrP-suppression studies attributable to the loss of PrP itself, or to the mechanism used to achieve that loss?
7. MDM2-linked microglial dysfunction in obsessive-compulsive disorder
8. Spatiotemporal development of sparse excitatory neuronal types within the deep mouse cortex
9. Integrated Single-cell and Bulk Transcriptome Analysis Characterizes a Candidate Ccl4/Lgals3/Egr1 Expression Pattern Associated with Immunometabolic Dysregulation in Traumatic Brain Injury
10. Detection of central nervous system tissues in minced meat by ELISA and histological examination
11. Histone Post-Translational Modifications at the Metabolism–Chromatin Interface: Reprogramming of Neuroinflammation in Alzheimer’s Disease
12. Serum Metabolomic Profiles Unveil Biomarkers and Core Metabolic Pathways in Multiple System Atrophy Patients
13. The Treadmill Prescription: The c-Fos–SIRT6 Epigenetic Axis as a Host-Encoded Bio-Medicine for Genomic Stability, Anti-Inflammation, and Lifespan Extension
14. EGR3 deletion attenuates developmental and epileptic encephalopathy in Kcna1 -null mice
15. Cell-Type-and Isoform-Specific Roles of Fatty Acid-Binding Proteins in Alzheimer’s Disease: An Evidence-to-Action Framework
16. uniSynK: a ratio-optimized bicistronic chemically induced dimerization tool for robust induction of dendritic spine enlargement
17. Advanced quantitative mapping of Alzheimer’s disease neuropathology and microglial activation in post-mortem hippocampal tissue
18. The Treadmill Prescription: The c-Fos–SIRT6 Epigenetic Axis as a Host-Encoded Bio-Medicine for Genomic Stability, Anti-Inflammation, and Lifespan Extension
19. Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice
20. Comparative Analysis of Plasma Biomarkers of Alzheimer’s Disease and Frontotemporal Dementia: The Dual Role of Soluble Fractalkine as a Biomarker of Frontotemporal Dementia and Its Neuroprotective Effects in Cortical Neurons “In Vitro”

Sub-Regions

• Single-cell and spatial transcriptomics — 39 papers
• Parkinson's Disease Mechanisms and Treatments — 32 papers
• Neurogenesis and neuroplasticity mechanisms — 20 papers
• Neuroinflammation and Neurodegeneration Mechanisms — 19 papers
• Neuroscience and Neuropharmacology Research — 18 papers
• Alzheimer's disease research and treatments — 14 papers