Latest Research in Click Chemistry and Applications

Top Research Topics in Click Chemistry and Applications

• Click Chemistry and Applications — 4 papers
• Synthesis and biological activity — 4 papers
• Sulfur-Based Synthesis Techniques — 2 papers
• Cancer therapeutics and mechanisms — 2 papers
• Quinazolinone synthesis and applications — 2 papers
• Diabetes Treatment and Management — 1 papers
• Mast cells and histamine — 1 papers
• Microbial Natural Products and Biosynthesis — 1 papers
• Histone Deacetylase Inhibitors Research — 1 papers
• Carbohydrate Chemistry and Synthesis — 1 papers

Highest-Cited Papers

1. Coumarin-triazole hybrids as potent low-toxicity anticancer agents evaluated by in vitro and in vivo 99mTc-MIBI uptake in glioblastoma models
2. Novel Sulfur-Containing Heterocycloalkyl Substituted Bicyclic Compounds as Viral DNA Polymerase Inhibitors for Treating Viral Infections, in particular, Herpesvirus Infections
3. Synthesis, Biological Evaluation, Molecular Docking, and Dynamics, DFT Studies of Amide-functionalized 1,2,3-Triazole-Acridone Conjugates
4. Synthesis and Biological Evaluation of 1,3,5-Triazine Derivatives for GPR119 Agonistic Activity
5. Exploratory scaffold hopping strategies led to identification of novel histamine H3 and H4 receptor ligands
6. Novel Lomefloxacin–Triazole Hybrids: Design, Synthesis and In Vitro Antiproliferative Activity in Breast, Melanoma and Colon Cancer Cell Lines
7. Synthesis and biological evaluation of novel dicarboximide-aryl/heteroarylpiperazine hybrid derivatives as anticancer agents
8. Synthesis, Chemical, and Biological Evaluation of Actinomycin Tetracyclic Oxazinone Derivatives and Application to Small-Molecule Drug Conjugates
9. Synthesis, molecular modelling, and biological evaluation of new pyrazine-oxadiazole hybrids as anticancer agents
10. Synthesis of Quinazoline Derivatives and Mechanistic Approaches in Lung and Breast Cancers
11. Anticancer Enzyme Inhibition Potential of Organosulphur Compounds via Histone Deacetylase, Carbonic Anhydrase, and Xanthine Oxidase Inhibition
12. Synthesis, Conformational Analysis, and Evaluation of 6 R - and 6 S -Methylmannoimidazoles as Mannosidase Inhibitors
13. α-Synuclein Binding Alkaloids from the Australian Bryozoan Amathia tricornis
14. Exploring the binding mechanism of 4-difluoromethyl pyrazole derivatives to cyclooxygenase-2: insights from DFT and molecular docking
15. The Pyrazolone Scaffold: A Privileged Motif for Molecular Hybridization in Drug Discovery
16. Oxadiazolone‐Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II‐Induced Vascular Contraction
17. Synthetic Strategies of Heterocycle‐Linked Sulfonamide Hybrids as Emerging Anticancer Agents: An Update
18. Synthesis and Broad-Spectrum Antiviral Evaluation of Novel 1,2,3-Triazole–Quinoline Derivatives Targeting SARS-CoV-2, Influenza, DENV-2, and CHIKV
19. s-triazine-based Derivatives as Anticancer Agents
20. Investigation of the In Vitro and In Silico Anticancer Potential of Novel 4‐Arylthiazole‐Hydrazone Derivatives