Latest Research in Computational Drug Discovery Methods

10 research papers · 2026 median publication year

Top Research Topics in Computational Drug Discovery Methods

Highest-Cited Papers

  1. TorchCraft: Unified binder design by inverting an all-atom structure predictor
  2. Conformational landscape of a macrocycle from REST enhanced sampling
  3. Deep Learning in Enzyme Function Prediction and Novel Enzyme Discovery
  4. Persistent Local Laplacian Prediction of Protein–Ligand Binding Affinities
  5. A curated benchmark for cofolding models on kinase conformational states
  6. Benchmarking Peptide-Protein Affinity Prediction Across Peptide and Target Shifts
  7. Physics-Informed Machine Learning for Prediction of Ligand Binding Kinetics: Leveraging Accelerated Molecular Dynamics Dynamic Fingerprints
  8. NMR Studies on Protein–Ligand Interactions
  9. Beyond Tokens: Probing Higher-Order Epistasis in Learned Protein Representations
  10. Siteomix: a PyMOL plugin for the detection, alignment, and similarity analysis of protein‒ligand binding sites
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L3 Region - - 2026 Sep Q3
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