Latest Research in Cancer, Hypoxia, and Metabolism

Top Research Topics in Cancer, Hypoxia, and Metabolism

• Cancer, Hypoxia, and Metabolism — 4 papers
• RNA modifications and cancer — 3 papers
• Mitochondrial Function and Pathology — 2 papers
• Hippo pathway signaling and YAP/TAZ — 1 papers
• Kruppel-like factors research — 1 papers
• Cancer-related gene regulation — 1 papers
• Nuclear Structure and Function — 1 papers
• Cancer, Stress, Anesthesia, and Immune Response — 1 papers
• Lung Cancer Treatments and Mutations — 1 papers
• Eosinophilic Esophagitis — 1 papers

Highest-Cited Papers

1. Targeting SHMT2 reverses lactate-driven CAF-mediated T-cell exclusion and sensitizes HNSCC to anti-PD-1 immunotherapy
2. YAP1 induces hepatocellular carcinoma via DNA demethylation rather than by canonical driver gene mutations
3. Epigenetic regulation of NLRP3 by ACLY–PLAC8 axis sustains metabolic adaptation in triple-negative breast cancer
4. Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma
5. ZDHHC4-mediated S-palmitoylation of CD276 promotes breast tumorigenesis
6. TEFM switches mPTP opening via interaction with VDAC1 to drive mtDNA stress and ESCC progression
7. A bipartite, mutation-tolerant NLS regulates interaction of ΔNp63α with importin alpha, nuclear transport and transcriptional activity
8. circNfix attenuates acute kidney injury by driving m6A-dependent degradation of YTHDF2 to stabilize DAPK2 mRNA
9. LACTB2 Promotes the Growth and Migration of Non‐Small Cell Lung Cancer By Regulating Mitochondrial Function
10. IDH3-dependent mitochondrial function in stromal fibroblasts suppresses malignant tumor growth
11. Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling
12. Targeting PGAM1 Y119 Phosphorylation Resensitizes Non-Small Cell Lung Cancer to Cisplatin Therapy by Promoting Oxidative Stress and DNA Damage
13. YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer
14. Dysregulated IL-2 signaling and T-cell subset shifts are associated with eosinophilic esophagitis activity
15. p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3
16. Symbiotic cancer cell-stroma crosstalk in the acidic tumor microenvironment