Latest Research in Single-cell and spatial transcriptomics

37 research papers · 0.0 average citations · 2026 median publication year

Top Research Topics in Single-cell and spatial transcriptomics

Highest-Cited Papers

  1. PLAU orchestrates pancreatic cancer progression via PI3K/AKT/mTORC1-mediated upregulation of MMP2/9 and FSCN1
  2. Integrated transcriptomic and single cell analyses identify matrix stiffness-related candidate prognostic genes and epithelial dynamics in colorectal cancer
  3. Midazolam Reduces Metabolic Viability and Induces Apoptosis in MIA PaCa-2 Pancreatic Cancer Cells with Selective Transcriptional Modulation of Wnt and Hedgehog Components: A Preliminary In Vitro Study
  4. Machine learning reveals diverse cell death patterns in colorectal cancer prognosis and therapy
  5. A microRNA-pair signature for prognosis and immune modulation in gastric cancer
  6. Patient-specific integration of RNA expression, methylation-derived replication-timing proxies, and histomorphology for pancreatic cancer subtyping
  7. Novel drug target ADAM8/17 is associated with the occurrence of intrahepatic cholangiocarcinoma via Notch1/Integrinα5 pathway
  8. RIPK3 overcomes 5-fluorouracil resistance in colorectal cancer cells via AKT/mTOR-mediated autophagy
  9. MATR3 promotes proliferation and invasion of colon adenocarcinoma cells: bulk, single-cell transcriptomic analysis and experimental validation
  10. GNG4 associated with tumor immune exclusion and compromised CD8+ T cell infiltration via microenvironmental crosstalk in hepatocellular carcinoma
  11. Radiogenomic identification of NET score-associated immune regulatory candidates in hepatocellular carcinoma
  12. Integrated Multi-Omics Analysis Reveals Candidate Serum Biomarkers Linked to Cancer-Associated Fibroblast-Mediated Extracellular Matrix Remodeling in Metastatic Gastric Cancer
  13. Integrative Multi-Omics Analysis Reveals Host Regulatory and Immune Networks with Inferred Dysbiosis Relevance in Colorectal Cancer
  14. Metastatic immune microenvironment remodeling by malignant epithelial cells drives colorectal cancer hepatic metastasis: Multi-omics insights
  15. SFRP4 is a novel prognostic biomarker associated with tumor microenvironment and immune cell infiltration in uterine corpus endometrial cancer
  16. Protein Variability Patterns in Ovarian Serous Carcinoma
  17. MYEOV promotes pancreatic cancer progression through an FGFR3 associated MAPK signaling pathway
  18. Lineage-Specific CagA Binding Mechanics and Microenvironmental Rewiring in East Asian Gastric Carcinogenesis
  19. Integrated single-cell and bulk RNA sequencing analysis reveals a TPM1-positive myCAF-associated gene signature predicting pancreatic cancer prognosis
  20. Keratin conversion signature (KRT13/KRT4) defines a high-risk pancreatic cancer subtype with extensive malignant phenotypes
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L3 Region - - 2026 Sep Q3

Single-cell and spatial transcriptomics

37 papers

Top Topics (10)

Ferroptosis and cancer prognosis8
Single-cell and spatial transcriptomics4
Pancreatic and Hepatic Oncology Research2
RNA Research and Splicing2
Helicobacter pylori-related gastroenterology studies2
Cancer Immunotherapy and Biomarkers2
PI3K/AKT/mTOR signaling in cancer1
Cancer, Stress, Anesthesia, and Immune Response1
MicroRNA in disease regulation1
Cholangiocarcinoma and Gallbladder Cancer Studies1

Top Publications (20)

1.PLAU orchestrates pancreatic cancer progression via PI3K/AKT/mTORC1-mediated upregulation of MMP2/9 and FSCN12.Integrated transcriptomic and single cell analyses identify matrix stiffness-related candidate prognostic genes and epithelial dynamics in colorectal cancer3.Midazolam Reduces Metabolic Viability and Induces Apoptosis in MIA PaCa-2 Pancreatic Cancer Cells with Selective Transcriptional Modulation of Wnt and Hedgehog Components: A Preliminary In Vitro Study4.Machine learning reveals diverse cell death patterns in colorectal cancer prognosis and therapy5.A microRNA-pair signature for prognosis and immune modulation in gastric cancer6.Patient-specific integration of RNA expression, methylation-derived replication-timing proxies, and histomorphology for pancreatic cancer subtyping7.Novel drug target ADAM8/17 is associated with the occurrence of intrahepatic cholangiocarcinoma via Notch1/Integrinα5 pathway8.RIPK3 overcomes 5-fluorouracil resistance in colorectal cancer cells via AKT/mTOR-mediated autophagy9.MATR3 promotes proliferation and invasion of colon adenocarcinoma cells: bulk, single-cell transcriptomic analysis and experimental validation10.GNG4 associated with tumor immune exclusion and compromised CD8+ T cell infiltration via microenvironmental crosstalk in hepatocellular carcinoma11.Radiogenomic identification of NET score-associated immune regulatory candidates in hepatocellular carcinoma12.Integrated Multi-Omics Analysis Reveals Candidate Serum Biomarkers Linked to Cancer-Associated Fibroblast-Mediated Extracellular Matrix Remodeling in Metastatic Gastric Cancer13.Integrative Multi-Omics Analysis Reveals Host Regulatory and Immune Networks with Inferred Dysbiosis Relevance in Colorectal Cancer14.Metastatic immune microenvironment remodeling by malignant epithelial cells drives colorectal cancer hepatic metastasis: Multi-omics insights15.SFRP4 is a novel prognostic biomarker associated with tumor microenvironment and immune cell infiltration in uterine corpus endometrial cancer16.Protein Variability Patterns in Ovarian Serous Carcinoma17.MYEOV promotes pancreatic cancer progression through an FGFR3 associated MAPK signaling pathway18.Lineage-Specific CagA Binding Mechanics and Microenvironmental Rewiring in East Asian Gastric Carcinogenesis19.Integrated single-cell and bulk RNA sequencing analysis reveals a TPM1-positive myCAF-associated gene signature predicting pancreatic cancer prognosis20.Keratin conversion signature (KRT13/KRT4) defines a high-risk pancreatic cancer subtype with extensive malignant phenotypes
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