Doctors vs. Algorithms: Physicians, too, struggle to learn from evidence that contradicts AI suggestions

Despite their widespread adoption, Artificial Intelligence-based Patient Classification Systems sometimes rely on incorrect, outdated, or incomplete data, which can lead to inaccurate outputs. Nevertheless, health professionals are expected to override these errors, at least when they have access to critical information. To test this, we conducted two experiments in which professional physicians interacted with an Artificial Intelligence system that incorrectly classified fictitious patients as either highly or lowly sensitive to a treatment. The physicians administered the treatment to a series of fictitious patients and received feedback that was useful for learning that the patient classification was incorrect and that all patients were equally sensitive to the treatment. We ran two experiments: in Experiment 1, the medicine showed medium effectiveness for both types of patients, while in Experiment 2, the treatment was completely ineffective for both types of patients. The results showed that, in the two experiments, physicians generally trusted the AI-based patient classification and struggled to learn from the evidence. Furthermore, in Experiment 2, they failed to realize that the treatment was ineffective. Our findings have important implications for healthcare professionals and patients, underscoring the need to critically evaluate Patient Classification Systems.

Authors

Institutions

Publication Details

Journal
PLOS Digital Health
Published
2026-07-09
DOI
https://doi.org/10.1371/journal.pdig.0001490
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Doctors vs. Algorithms: Physicians, too, struggle to learn from evidence that contradicts AI suggestions

Aranzazu Vinas, Helena Matute, Fernando Blanco
PLOS Digital Health
Artificial Intelligence in Healthcare and Education
article

Doctors vs. Algorithms: Physicians, too, struggle to learn from evidence that contradicts AI suggestions

Aranzazu Vinas, Helena Matute, Fernando Blanco
article en

Abstract

Despite their widespread adoption, Artificial Intelligence-based Patient Classification Systems sometimes rely on incorrect, outdated, or incomplete data, which can lead to inaccurate outputs. Nevertheless, health professionals are expected to override these errors, at least when they have access to critical information. To test this, we conducted two experiments in which professional physicians interacted with an Artificial Intelligence system that incorrectly classified fictitious patients as either highly or lowly sensitive to a treatment. The physicians administered the treatment to a series of fictitious patients and received feedback that was useful for learning that the patient classification was incorrect and that all patients were equally sensitive to the treatment. We ran two experiments: in Experiment 1, the medicine showed medium effectiveness for both types of patients, while in Experiment 2, the treatment was completely ineffective for both types of patients. The results showed that, in the two experiments, physicians generally trusted the AI-based patient classification and struggled to learn from the evidence. Furthermore, in Experiment 2, they failed to realize that the treatment was ineffective. Our findings have important implications for healthcare professionals and patients, underscoring the need to critically evaluate Patient Classification Systems.

PLOS Digital HealthVol. 5(7)
Universidad de Deusto (ES), University of the Basque Country (ES), Universidad de Granada (ES)
Ministerio de Ciencia, Innovación y Universidades, Eusko Jaurlaritza
Quality Education
Openalex Percentile: Top 11%
Artificial Intelligence in Healthcare and Education
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.