“An Open-Label Randomised Controlled Clinical Study to Evaluate the Efficacy of Apamarga Ksharaplota with Shweta Arka Ksharaplota in the Management of Kaphaja Dushta Vrana Vis-À-Vis Diabetic Foot Ulcer”.

Vrana and Vranaropana are considered essential aspects of Shalya Tantra in Ayurveda. Dushta Vrana or infected wound, occurs due to vitiation of Doshas and presents with foul smell, abnormal discolouration, excessive discharge, severe pain and delayed healing. Such wounds may involve damage to both skin and deeper tissues. Acharya Sushruta explained various dressing materials like Pichu, Plota, Kavalika and Vikeshika for cleansing, covering and managing wounds effectively1. The medicated Ksharaplota helps in the removal of unhealthy tissue, controls infection and promotes healthy granulation tissue formation, thereby enhancing the wound healing process. The Ksharaplota prepared from Apamaraga and Shweta Arka Ksharaplota is very effective in the management of Kaphaja Dustavrana. Materials and method: Clinically diagnosed cases of Kaphaja Dustavrana were selected for the styudy. Total 40 subjectes were selected for the study, and they were divided into Group A and Group B. Group A treated with Apamarga Ksharaplota and Group B was treated with Shweta Arka Ksharaplota until the attainment of Shudha vrana lakshana. Assesment done on 1st, 3rd, 5th and 7th day. Follow up on 21st and 42nd day. The result of the study was assessed with subjective and objective criteria through grading and appropriate statistical tests. Results: On the basis of the assessment criteria and overall results of the treatment, Both Apamarga Ksharaplota and Shweta Arka Ksharaplota showed statistically significant results in Diabetic Foot Ulcer by reducing pain, burning sensation, itching, discharge, odour, size of the wound and also development of granulation tissue which eventually resulted in wound healing. Conclusion: Apamarga Ksharaplota & Shweta Arka Ksharaplota dressing both are highly effective in the management of Kapaja Dushta Vrana.