Advanced Approaches in the Treatment of Autoimmune Thrombocytopenic Purpura: A Comparative Analysis of Conservative and Surgical Methods

Autoimmune thrombocytopenic purpura (ATP), alternatively designated as primary immune thrombocytopenia (ITP) or Werlhof's disease, is an immune-mediated hematological disorder characterized by accelerated antibody-coated platelet destruction and severely impaired megakaryocyte maturation. While conventional therapeutic strategies heavily rely on systemic oral/parenteral glucocorticosteroids and standard open splenectomy, both arms carry high risks of severe treatment-induced mo