Using Bayesian Evidence to Estimate District‐Wise Tuberculosis Incidence Rates, Missed Cases and Fraction of Treated Cases in Bangladesh

Undetected and untreated tuberculosis (TB) remains a serious public health challenge, which increases mortality and transmission within households and communities. This study estimates district-wise TB incidence rates, missed cases, and the fraction of treated cases in Bangladesh using a Bayesian approach. By integrating data from national TB notifications, TB-related mortality, prevalence surveys, and auxiliary sources in Bangladesh, we developed an analytical model that estimates district-level TB burden from 2008 to 2017. We used a Bayesian modelling approach, treating incidence as a hidden event inferred from other components. We included predictor variables in the analysis at two points in the model-incidence and fraction notified. Here, we estimate the number of missing TB cases across districts, allowing us to identify areas with high proportions of untreated cases. Our findings revealed notable spatial and temporal variation, with some districts showing consistently higher predicted incidence rates and others exhibiting lower detection or treatment coverage. However, treatment coverage showed clear regional disparities, with poorer districts recording substantially lower fractions of treated cases compared to wealthier districts. These findings highlight the need for policymakers to prioritise equitable resource allocation to mitigate the burden of TB in Bangladesh.

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Publication Details

Journal
Tropical Medicine & International Health
Published
2026-11-11
DOI
https://doi.org/10.1111/tmi.70252
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Using Bayesian Evidence to Estimate District‐Wise Tuberculosis Incidence Rates, Missed Cases and Fraction of Treated Cases in Bangladesh

Emma Sue McBryde, Alec S. Henderson, Samson T. Ogunlade, Md Abdul Kuddus et al.
Tropical Medicine & International Health
Tuberculosis Research and Epidemiology
article

Using Bayesian Evidence to Estimate District‐Wise Tuberculosis Incidence Rates, Missed Cases and Fraction of Treated Cases in Bangladesh

Emma Sue McBryde, Alec S. Henderson, Samson T. Ogunlade, Md Abdul Kuddus, Oyelola Abdulwasiu Adegboye
article en

Abstract

Undetected and untreated tuberculosis (TB) remains a serious public health challenge, which increases mortality and transmission within households and communities. This study estimates district-wise TB incidence rates, missed cases, and the fraction of treated cases in Bangladesh using a Bayesian approach. By integrating data from national TB notifications, TB-related mortality, prevalence surveys, and auxiliary sources in Bangladesh, we developed an analytical model that estimates district-level TB burden from 2008 to 2017. We used a Bayesian modelling approach, treating incidence as a hidden event inferred from other components. We included predictor variables in the analysis at two points in the model-incidence and fraction notified. Here, we estimate the number of missing TB cases across districts, allowing us to identify areas with high proportions of untreated cases. Our findings revealed notable spatial and temporal variation, with some districts showing consistently higher predicted incidence rates and others exhibiting lower detection or treatment coverage. However, treatment coverage showed clear regional disparities, with poorer districts recording substantially lower fractions of treated cases compared to wealthier districts. These findings highlight the need for policymakers to prioritise equitable resource allocation to mitigate the burden of TB in Bangladesh.

Tropical Medicine & International Health
Inserm (FR), The University of Queensland (AU), Australian Institute of Tropical Health and Medicine (AU), Charles Darwin University (AU), Menzies School of Health Research (AU), James Cook University (AU), University of Rajshahi (BD)
Tuberculosis Research and Epidemiology
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