Knowledge, Attitudes, Practices and Determinants of Measles Vaccination among Mothers of Under-Five Children in Agege Local Government Area, Lagos State, Nigeria

Background: Measles remains an important vaccine-preventable cause of childhood morbidity and mortality where vaccination is delayed or incomplete. This study assessed maternal knowledge and attitudes, measles vaccination uptake, and determinants of uptake among mothers of under-five children in Agege Local Government Area (LGA), Lagos State, Nigeria. Methods: A facility-based descriptive cross-sectional study was conducted among 308 mothers of under-five children selected through a multistage sampling procedure. Data were collected with a structured interviewer-administered questionnaire and analysed using JASP version 0.98.1. Descriptive statistics, chi-square tests, Cramer's V, odds ratios with 95% confidence intervals (CIs), and multivariable logistic regression were used; statistical significance was set at p < .05. Results: Mean maternal age was 33.7 ± 8.5 years. Good knowledge was recorded in 267 (87%) respondents and 303 (98%) had a positive attitude. Overall measles vaccination uptake was adequate among 282 (92%), although 97 (32%) reported a missed vaccination appointment and 112 (36.4%) reported incomplete scheduled immunization. Knowledge was associated with uptake (χ² = 15.57, p < .001), whereas attitude was not (χ² = 0.469, p = .494). In the adjusted model, occupation, number of under-five children, knowledge status, waiting time, work schedule, information gaps, cultural beliefs, family-elder influence, religious beliefs and community norms were statistically significant (p < .05); several estimates had very wide CIs and therefore require cautious interpretation. Conclusion: Maternal knowledge, attitudes and reported measles vaccination uptake were high, but missed appointments, incomplete immunization and practical, informational and sociocultural barriers persisted. Programmes should combine accurate health education with shorter waiting times, flexible service delivery, defaulter tracking and family/community engagement.