Association between TyG‑BMI and repeat percutaneous coronary intervention (PCI) risk: exploratory stratification by glucose metabolism status

Most patients undergoing percutaneous coronary intervention (PCI) are diagnosed with coronary heart disease (CHD). The triglyceride glucose‑body mass index (TyG‑BMI) has been reported to be associated with CHD. This study aimed to investigate the association between TyG‑BMI and the risk of repeat PCI among post‑PCI patients, with additional exploratory stratification analyses according to glucose‑metabolism status. Data for this study were derived from resident health‑record follow‑up records of Yipeng Community Health Service Center, covering January 2015 to January 2025. Logistic regression models and restricted cubic spline (RCS) were used to evaluate the association between TyG‑BMI and the risk of repeat PCI among post‑PCI patients, with exploratory stratification by glucose‑metabolism status. Logistic regression and restricted cubic spline analyses showed no significant linear or nonlinear association between TyG‑BMI and repeat PCI ( OR =0.999, 95%CI :0.994 ~ 1.003, P = 0.534; nonlinear χ 2 = 0.91, df = 3, P = 0.8223). Stratified analyses by glucose metabolism status also revealed no significant correlation in any stratum( P > 0.05). No independent association between TyG‑BMI and repeat PCI was identified in post‑PCI patients, even within different glucose‑metabolism strata. Relevant findings require further verification in larger prospective cohorts.