GALACTOSE METABOLISM AND ITS IMPORTANCE IN THE HUMAN BODY

This article examines the biochemical processes of galactose metabolism and its significance in the human body. Particular attention is paid to the Leloir pathway, which is the main route of galactose utilization in the liver. The article describes the main stages of galactose conversion, the functions of key enzymes involved in this process, and the role of galactose in energy metabolism and the synthesis of glycoproteins and glycolipids. It also discusses the biochemical mechanisms of galactose metabolism disorders, particularly classic galactosemia, which develops as a result of galactose-1-phosphate uridylyltransferase deficiency. Understanding these metabolic processes is essential for studying carbohydrate metabolism, identifying inherited metabolic disorders, and improving their early diagnosis and prevention of complications.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-11
DOI
https://doi.org/10.5281/zenodo.24127968
Primary Topic
Metabolism and Genetic Disorders
Type
article
Field-Weighted Citation Impact
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article

GALACTOSE METABOLISM AND ITS IMPORTANCE IN THE HUMAN BODY

Riksiyeva Umida, Azimjonov
Zenodo (CERN European Organization for Nuclear Research)
Metabolism and Genetic Disorders
article

GALACTOSE METABOLISM AND ITS IMPORTANCE IN THE HUMAN BODY

Riksiyeva Umida, Azimjonov
article en

Abstract

This article examines the biochemical processes of galactose metabolism and its significance in the human body. Particular attention is paid to the Leloir pathway, which is the main route of galactose utilization in the liver. The article describes the main stages of galactose conversion, the functions of key enzymes involved in this process, and the role of galactose in energy metabolism and the synthesis of glycoproteins and glycolipids. It also discusses the biochemical mechanisms of galactose metabolism disorders, particularly classic galactosemia, which develops as a result of galactose-1-phosphate uridylyltransferase deficiency. Understanding these metabolic processes is essential for studying carbohydrate metabolism, identifying inherited metabolic disorders, and improving their early diagnosis and prevention of complications.

Zenodo (CERN European Organization for Nuclear Research)
Metabolism and Genetic Disorders
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