The adaptation of insulin clearance to metabolic demand is a key determinant of glucose tolerance - A review of the evidence

Human clamp and oral glucose tolerance studies in 368 adults show insulin clearance falls after glucose intake; the response is blunted in type 2 diabetes.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-11
DOI
https://doi.org/10.5281/zenodo.24140520
Primary Topic
Pancreatic function and diabetes
Type
article
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article

The adaptation of insulin clearance to metabolic demand is a key determinant of glucose tolerance - A review of the evidence

Conte Antonio
Zenodo (CERN European Organization for Nuclear Research)
Pancreatic function and diabetes
article

The adaptation of insulin clearance to metabolic demand is a key determinant of glucose tolerance - A review of the evidence

Conte Antonio
article en

Abstract

Human clamp and oral glucose tolerance studies in 368 adults show insulin clearance falls after glucose intake; the response is blunted in type 2 diabetes.

Zenodo (CERN European Organization for Nuclear Research)
Pancreatic function and diabetes
DOIOpen Access PDFOpenAlex
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The adaptation of insulin clearance to metabolic demand is a key determinant of glucose tolerance - A review of the evidence — Conte Antonio · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS