National Trends in Congenital Syphilis Among US Newborns, 2012-2022.
Congenital syphilis among US birth hospitalizations increased 5.9-fold (95% CI = 4.9-7.2) from 2012 to 2022 in the Kids' Inpatient Database. Increases were observed across all demographics, income levels, and hospital settings, with the largest increase among Native Americans (21.5-fold; 95% CI = 8.8-52.1). These findings underscore the need for improved syphilis prevention and prenatal screening efforts.
Authors
- Thomas C. Quinn (ORCID: https://orcid.org/0000-0002-0404-1315)
- Eshan U. Patel (ORCID: https://orcid.org/0000-0003-2174-5004)
- Matthew M. Hamill (ORCID: https://orcid.org/0000-0002-1277-819X)
- Aaron A.R. Tobian (ORCID: https://orcid.org/0000-0002-0517-3766)
- M. Kate Grabowski (ORCID: https://orcid.org/0000-0002-4451-3436)
- Ping Yang
- Xianming Zhu
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- PubMed
- Published
- 2026-11-11
- DOI
- https://doi.org/10.1093/cid/ciag588
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00