A Granularity Blind Spot in the Evaluation of SNOMED CT Concept Normalization
Abstract Background. Clinical concept normalization maps free-text mentions to terminology codes but is usually evaluated with aggregate exact match and a binary seen/novel split. These summaries do not distinguish mentions recorded as finer-grained than their assigned code. Using native granularity labels in three Spanish SNOMED CT corpora, we tested whether exact-match error incidence differs between NARROW and EXACT reference strata across up to five lexical, neural and generative systems. Results. Systems failed to reproduce the corpus-assigned code under exact match more often for NARROW mentions (finer-grained than their assigned code) than for EXACT mentions (panel-weighted Mantel–Haenszel risk ratio 1.72, 95% CI 1.63–1.83). The Wu–Palmer-minus-exact credit gap was larger on NARROW mentions in all 14 system×benchmark cells (geometric mean ratio 1.87, 95% CI 1.71–2.05), driven by error incidence rather than a consistent difference in conditional error proximity. In the pooled Qwen analysis, sibling and cousin predictions contributed 56–67% of summed Wu–Palmer credit among non-exact predictions. Under a stricter same-lineage criterion, the uplift beyond exact match was larger for NARROW mentions in 9 of 14 cells. The larger graded gap retained its direction under alternative metrics, candidate spaces and xMEN. Graph-refined novelty classified 825 of 982 code-novel DisTEMIST mentions (84.0%) as ancestor-seen; the remaining 157 were fully isolated (6.3% of all 2,507 mentions). Majority-vote consensus in the blinded three-rater audit agreed with the corpus labels for 130 of 150 mentions (κ = 0.73). Conclusions. Aggregate exact match obscures a benchmark-relative difference between reference-granularity strata. For benchmarks with granularity labels, granularity-stratified exact-match error rates should be reported first; hierarchy-aware scores should be paired with relation types.
Authors
- Yoojin Nam (ORCID: https://orcid.org/0000-0001-8565-1360)
- Pa Hong (ORCID: https://orcid.org/0000-0001-5495-5230)
- Eunji Kim (ORCID: https://orcid.org/0009-0003-3075-9683)
- Yejin Jo (ORCID: https://orcid.org/0009-0002-0158-7950)
- YangWon Kim
Institutions
- Asan Medical Center (KR)
- University of Ulsan (KR)
- Samsung Changwon Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Research Square
- Published
- 2026-11-11
- DOI
- https://doi.org/10.21203/rs.3.rs-10602575/v1
- Primary Topic
- Biomedical Text Mining and Ontologies
- Type
- preprint