Eyelid Margin Myxoma: A Rare Case Report and Literature Review

Abstract: Eyelid margin myxomas are rare benign tumors that may presage Carney complex before potentially lethal cardiac manifestations develop. We report a 59-year-old woman with an enlarging left lower eyelid margin lesion, clinically suspicious for malignancy. Excisional biopsy with histopathological and immunohistochemical evaluation confirmed myxoma. Personal and family histories revealed no features suggestive of Carney complex, and no local recurrence was observed at 3-month follow-up. This case highlights the diagnostic challenge of eyelid margin myxomas and the oculoplastic surgeon’s opportunity to recognize a cutaneous clue to clinically significant systemic disease.