Supersaturated Oxygen Therapy for Refractory No‐Reflow Following PCI for Non–ST‐Elevation ACS

No-reflow is high-risk complication of PCI, associated with larger infarct size, ventricular dysfunction, and mortality. We describe a 62-year-old man with a distal RCA lesion who developed refractory no-reflow despite extensive pharmacologic therapy and thrombectomy. Supersaturated oxygen therapy, used as a bail-out strategy, restored distal perfusion and may represent an emerging option for patients with severe, treatment-resistant no-reflow.

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Publication Details

Journal
Catheterization and Cardiovascular Interventions
Published
2026-11-10
DOI
https://doi.org/10.1002/ccd.70961
Primary Topic
Coronary Interventions and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Supersaturated Oxygen Therapy for Refractory No‐Reflow Following PCI for Non–ST‐Elevation ACS

Emmanouil S. Brilakis, Pedro E P Carvalho, Yader B. Sandoval, Jay H. Traverse
Catheterization and Cardiovascular Interventions
Coronary Interventions and Diagnostics
article

Supersaturated Oxygen Therapy for Refractory No‐Reflow Following PCI for Non–ST‐Elevation ACS

Emmanouil S. Brilakis, Pedro E P Carvalho, Yader B. Sandoval, Jay H. Traverse
article en

Abstract

No-reflow is high-risk complication of PCI, associated with larger infarct size, ventricular dysfunction, and mortality. We describe a 62-year-old man with a distal RCA lesion who developed refractory no-reflow despite extensive pharmacologic therapy and thrombectomy. Supersaturated oxygen therapy, used as a bail-out strategy, restored distal perfusion and may represent an emerging option for patients with severe, treatment-resistant no-reflow.

Catheterization and Cardiovascular Interventions
Abbott Northwestern Hospital (US), Minneapolis Heart Institute Foundation (US)
Coronary Interventions and Diagnostics
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