ACEF-TAAD: three requested analyses

This repository contains a consolidated R script for three analyses of the ACEF-TAAD score: nomogram construction, bootstrap internal validation, and decision-curve analysis. The script uses the rms package to construct the nomogram and perform 1,000 bootstrap resamples, with predictors and biomarker cutoffs held fixed while regression coefficients are re-estimated. Decision-curve analysis uses the rmda package to assess net benefit in the training and external test sets using the model fitted in the training set. The archive includes the R script, a README, a variable dictionary, and an empty input template. Patient-level data are not included. This script was consolidated during manuscript revision and has not yet been execution-verified in R.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-10
DOI
https://doi.org/10.5281/zenodo.24102175
Primary Topic
Statistical Methods in Epidemiology
Type
article
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article

ACEF-TAAD: three requested analyses

Linfeng Xie
Zenodo (CERN European Organization for Nuclear Research)
Statistical Methods in Epidemiology
article

ACEF-TAAD: three requested analyses

Linfeng Xie
article en

Abstract

This repository contains a consolidated R script for three analyses of the ACEF-TAAD score: nomogram construction, bootstrap internal validation, and decision-curve analysis. The script uses the rms package to construct the nomogram and perform 1,000 bootstrap resamples, with predictors and biomarker cutoffs held fixed while regression coefficients are re-estimated. Decision-curve analysis uses the rmda package to assess net benefit in the training and external test sets using the model fitted in the training set. The archive includes the R script, a README, a variable dictionary, and an empty input template. Patient-level data are not included. This script was consolidated during manuscript revision and has not yet been execution-verified in R.

Zenodo (CERN European Organization for Nuclear Research)
Statistical Methods in Epidemiology
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