Food Addiction and Psychiatric Comorbidity: A Latent Profile Analysis

OBJECTIVE: Food addiction (FA) frequently co-occurs with eating disorders (EDs), PTSD, mood/anxiety disorders, and substance use disorders (SUDs), yet few studies have examined clinically meaningful subgroups in multi-morbid treatment populations. Latent profile analysis (LPA) was used to identify subgroups in a highly comorbid sample to determine whether FA marks a distinct profile. METHOD: Seven hundred and forty seven adults admitted to a multi-site behavioral health center completed self-report measures of PTSD, complex PTSD, dissociation, depression, anxiety, substance use, ED, and FA. These nine indicators were reduced to four composites (Trauma/Internalizing, ED, FA, and other substance use) and submitted to LPA in R; a parallel analysis entering all nine indicators individually served as a robustness check. Models were fit for one to six profiles, selected on BIC, entropy, minimum profile size, and interpretability, then validated against demographics, diagnoses, and distal outcomes. RESULTS: A three-profile conditional-independence (EEI) solution fit best: Trauma/Internalizing/ED (23%), lower-acuity (65%), and FA (12%). The FA profile had by far the highest FA severity and body mass index (BMI) but did not differ from the Trauma/Internalizing/ED profile on ED or Trauma/Internalizing severity. The lower-acuity profile comprised most patients, with lower symptomatology and markedly better quality of life. The nine-indicator model recovered the FA profile essentially unchanged, while remaining patients were split by alcohol use rather than acuity. DISCUSSION: FA marks a distinct clinical subtype within trauma-burdened psychiatric populations rather than a uniform feature of ED or severe trauma, supporting routine screening and integrated treatment addressing FA alongside PTSD and ED pathology.

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Publication Details

Journal
International Journal of Eating Disorders
Published
2026-11-09
DOI
https://doi.org/10.1002/eat.70264
Primary Topic
Eating Disorders and Behaviors
Type
article
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article

Food Addiction and Psychiatric Comorbidity: A Latent Profile Analysis

Timothy D. Brewerton, Kimberly D. Dennis, Cindy Nguyen, Dean Bilenker
International Journal of Eating Disorders
Eating Disorders and Behaviors
article

Food Addiction and Psychiatric Comorbidity: A Latent Profile Analysis

Timothy D. Brewerton, Kimberly D. Dennis, Cindy Nguyen, Dean Bilenker
article en

Abstract

OBJECTIVE: Food addiction (FA) frequently co-occurs with eating disorders (EDs), PTSD, mood/anxiety disorders, and substance use disorders (SUDs), yet few studies have examined clinically meaningful subgroups in multi-morbid treatment populations. Latent profile analysis (LPA) was used to identify subgroups in a highly comorbid sample to determine whether FA marks a distinct profile. METHOD: Seven hundred and forty seven adults admitted to a multi-site behavioral health center completed self-report measures of PTSD, complex PTSD, dissociation, depression, anxiety, substance use, ED, and FA. These nine indicators were reduced to four composites (Trauma/Internalizing, ED, FA, and other substance use) and submitted to LPA in R; a parallel analysis entering all nine indicators individually served as a robustness check. Models were fit for one to six profiles, selected on BIC, entropy, minimum profile size, and interpretability, then validated against demographics, diagnoses, and distal outcomes. RESULTS: A three-profile conditional-independence (EEI) solution fit best: Trauma/Internalizing/ED (23%), lower-acuity (65%), and FA (12%). The FA profile had by far the highest FA severity and body mass index (BMI) but did not differ from the Trauma/Internalizing/ED profile on ED or Trauma/Internalizing severity. The lower-acuity profile comprised most patients, with lower symptomatology and markedly better quality of life. The nine-indicator model recovered the FA profile essentially unchanged, while remaining patients were split by alcohol use rather than acuity. DISCUSSION: FA marks a distinct clinical subtype within trauma-burdened psychiatric populations rather than a uniform feature of ED or severe trauma, supporting routine screening and integrated treatment addressing FA alongside PTSD and ED pathology.

International Journal of Eating Disorders
Medical University of South Carolina (US), Loyola University Chicago (US), University of Illinois Chicago (US), Columbia University (US)
Eating Disorders and Behaviors
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