Can amitriptyline result in tardive parkinsonism and akathisia?

No direct evidence for amitriptyline causing tardive parkinsonism was identified, but it is associated with akathisia and other movement disorders. Clinicians should monitor for these effects in patients using amitriptyline.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-11-09
DOI
https://doi.org/10.5281/zenodo.24082844
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Can amitriptyline result in tardive parkinsonism and akathisia?

Tripdatabase
Zenodo (CERN European Organization for Nuclear Research)
Parkinson's Disease Mechanisms and Treatments
article

Can amitriptyline result in tardive parkinsonism and akathisia?

Tripdatabase
article en

Abstract

No direct evidence for amitriptyline causing tardive parkinsonism was identified, but it is associated with akathisia and other movement disorders. Clinicians should monitor for these effects in patients using amitriptyline.

Zenodo (CERN European Organization for Nuclear Research)
Parkinson's Disease Mechanisms and Treatments
DOIOpen Access PDFOpenAlex
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Can amitriptyline result in tardive parkinsonism and akathisia? — Tripdatabase · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS