Localisation pulmonaire volumineuse, nécrosée et surinfectée d'un probable choriocarcinome gestationnel : place et limites de la chirurgie thoracique, à propos d'un cas et revue de la littérature

Background: Gestational choriocarcinoma is a malignant trophoblastic tumor. It is an aggressive neoplasm, with the lungs being the main site of metastasis. As this tumor is highly chemosensitive, the management of pulmonary metastases rarely involves thoracic surgery. Case presentation: We report the case of a large, necrotic, and infected pulmonary lesion secondary to a gestational choriocarcinoma, diagnosed five years after a molar pregnancy in a 39-year-old woman. The clinical outcome was unfavorable despite combined management with pleuropneumonectomy and adjuvant chemotherapy. Objective: This case serves as the basis for a narrative review of the literature on the role and limitations of thoracic surgery in the management of pulmonary metastases from gestational choriocarcinoma.

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Publication Details

Journal
Journal of African clinical cases and reviews.
Published
2026-11-09
DOI
https://doi.org/10.70065/2624.jaccrsurg.002l010911
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
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article

Localisation pulmonaire volumineuse, nécrosée et surinfectée d'un probable choriocarcinome gestationnel : place et limites de la chirurgie thoracique, à propos d'un cas et revue de la littérature

W. Ngatchou Djomo, DD Banga Nkomo, SN Chuente Sime, J Sango et al.
Journal of African clinical cases and reviews.
Gestational Trophoblastic Disease Studies
article

Localisation pulmonaire volumineuse, nécrosée et surinfectée d'un probable choriocarcinome gestationnel : place et limites de la chirurgie thoracique, à propos d'un cas et revue de la littérature

W. Ngatchou Djomo, DD Banga Nkomo, SN Chuente Sime, J Sango, AL Ntyo'o Nkoumou, A Ndoumba, F Atemkeng Tsatedem
article en

Abstract

Background: Gestational choriocarcinoma is a malignant trophoblastic tumor. It is an aggressive neoplasm, with the lungs being the main site of metastasis. As this tumor is highly chemosensitive, the management of pulmonary metastases rarely involves thoracic surgery. Case presentation: We report the case of a large, necrotic, and infected pulmonary lesion secondary to a gestational choriocarcinoma, diagnosed five years after a molar pregnancy in a 39-year-old woman. The clinical outcome was unfavorable despite combined management with pleuropneumonectomy and adjuvant chemotherapy. Objective: This case serves as the basis for a narrative review of the literature on the role and limitations of thoracic surgery in the management of pulmonary metastases from gestational choriocarcinoma.

Journal of African clinical cases and reviews.Vol. 2(4)
Université de Yaoundé I (CM), University of Douala (CM), Université de Dschang (CM)
Gestational Trophoblastic Disease Studies
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