Note No. 22 from the series "Cosmobiology of Mirny": Induction under Penrose's bush — where consciousness actually hides. Proteomic architecture of the thinking medium (9606-Brain)

This work transfers the MP2DS quantitative analysis framework to human thinking tissue (9606-Brain) using integrated PaxDb 5.0 datasets. A critical scale gap (more than 700-fold) is revealed between the passive cytoskeletal scaffold of neurons (MAP2, 8,500 ppm) and the marginal carriers of hysteretic memory (DHFR, 12 ppm) and synaptic induction (DLG4, CAMK2A). Consciousness is formalized as a property of the precision position of rare regulatory elements of an elastic medium, rather than the mass of its scaffold. The quantum-microtubular hypothesis of Roger Penrose postulates a key role for microtubules in generating the phenomenon of consciousness. However, a total proteomic scan of brain tissue refutes this approach. The protein MAP2 occupies a colossal 8,500 ppm (13.43% of the entire mass of the detected brain proteome), performing the function of a mechanical framework and transport rails. Trying to explain the origin of consciousness and induction through the mass of microtubules is like explaining the essence of program code by the thickness of the copper wires inside a system unit. The true regulators of the temporal step of the medium are pushed into the marginal "long tail" of the distribution.