Development of Bolus Made from Silicone Rubber, Glycerol-Gelatin, and Aloe Vera-Gelatin Gel in Post-Mastectomy Breast Cancer Radiotherapy

This study aims to develop and compare the physical, dosimetric, and applicative characteristics of boluses made from silicone rubber, glycerol-gelatin, and aloe vera-gelatin gel for post-mastectomy breast cancer radiotherapy. The study used an experimental method with variations in material composition and thickness. The samples were boluses of the three materials, while the testing instruments and procedures included measuring relative electron density (RED), surface dose, homogeneity, and evaluating applicative characteristics. Data were analyzed descriptively by comparing the measurement results of each material with a comparison bolus and considering aspects of cost, setting time, form durability, and hygiene. The results showed that silicone rubber was superior in form durability and stability, but had the highest estimated manufacturing cost. Glycerol-gelatin showed advantages in terms of cost and increased surface dose, especially at a ratio of 2:3 with a thickness of 1.5 cm. Aloe vera-gelatin gel also has the potential to be an alternative material by considering the balance of physical and dosimetric characteristics. In conclusion, the three materials have different advantages and limitations, so their selection needs to be adjusted to dosimetric needs, applicative aspects, and costs. Further validation under conditions closer to clinical practice is necessary before routine implementation.