Spontaneous Disappearance of Moyamoya Disease Complicated With Intracranial Aneurysm

Moyamoya disease (MMD) is a rare chronic progressive cerebrovascular occlusive disease, which is mainly characterized by bilateral stenosis or occlusion of the ends of the internal carotid arteries and abnormal moyamoya collateral vascular network formation in the brain base. The annual incidence is 1.14 cases per 100000 people. About 3.4% to 14.8% of patients with MMD will have intracranial aneurysms, which are an important risk factor for intracranial hemorrhage. In clinical practice, MMD complicated by aneurysms often requires surgical intervention, and spontaneous complete disappearance of aneurysms is extremely rare. We report a case of hemorrhagic MMD complicated by an intracranial aneurysm. After conservative treatment, the follow-up cerebral angiography showed that the intracranial aneurysm disappeared spontaneously and completely, and the prognosis of the patient was good. This report hopes to provide references for the individualized treatment of MMD complicated by intracranial aneurysms.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2026-11-09
DOI
https://doi.org/10.1097/scs.0000000000013580
Primary Topic
Moyamoya disease diagnosis and treatment
Type
article
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article

Spontaneous Disappearance of Moyamoya Disease Complicated With Intracranial Aneurysm

Ren-xing Song, 张一鸣, Hui Guo
Journal of Craniofacial Surgery
Moyamoya disease diagnosis and treatment
article

Spontaneous Disappearance of Moyamoya Disease Complicated With Intracranial Aneurysm

Ren-xing Song, 张一鸣, Hui Guo
article en

Abstract

Moyamoya disease (MMD) is a rare chronic progressive cerebrovascular occlusive disease, which is mainly characterized by bilateral stenosis or occlusion of the ends of the internal carotid arteries and abnormal moyamoya collateral vascular network formation in the brain base. The annual incidence is 1.14 cases per 100000 people. About 3.4% to 14.8% of patients with MMD will have intracranial aneurysms, which are an important risk factor for intracranial hemorrhage. In clinical practice, MMD complicated by aneurysms often requires surgical intervention, and spontaneous complete disappearance of aneurysms is extremely rare. We report a case of hemorrhagic MMD complicated by an intracranial aneurysm. After conservative treatment, the follow-up cerebral angiography showed that the intracranial aneurysm disappeared spontaneously and completely, and the prognosis of the patient was good. This report hopes to provide references for the individualized treatment of MMD complicated by intracranial aneurysms.

Journal of Craniofacial Surgery
Weifang People's Hospital (CN)
Moyamoya disease diagnosis and treatment
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Spontaneous Disappearance of Moyamoya Disease Complicated With Intracranial Aneurysm — Ren-xing Song, 张一鸣, et al. · Journal of Craniofacial Surgery (2026) | TGRS Research Map | TGRS