Relationship Between Post‐Operative Complications and Length of Stay in Patients Requiring Free Flap Reconstruction of the Head and Neck

BACKGROUND: Reconstructive with free flap procedures are often required following ablative removal of pathologies from the head and neck. The Clavien-Dindo Classification (CDC) system is widely used to grade complication severity; however, there are limited studies examining the relationship between complications and length of stay (LOS) in this cohort. PURPOSE: To evaluate the association between complication severity and both hospital and intensive care unit (ICU) LOS in patients undergoing head and neck free flap reconstruction. METHODS: This retrospective cohort study included 994 patients treated between 2016 and 2024. Complications were graded using the CDC system. LOS was analysed using generalised linear models with a Gamma distribution and log-link. Kruskal-Wallis tests were used for supplementary analysis. RESULTS: Complications occurred in 54.5% of patients. Higher CDC grades were significantly associated with longer ICU (p < 0.001) and hospital LOS (p < 0.001). CDC Grades II, IIIb and IVa were independently associated with prolonged ICU LOS. All CDC grades were associated with increased hospital LOS. CONCLUSION: This study provides outcome data linking complication severity to ICU and hospital LOS. The CDC, while advantageous, fails to separate significant negative outcomes, such as free flap failure from a more simple return to theatre. Modifications may further improve distinction in complications and effect on overall hospital stay.

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Publication Details

Journal
ANZ Journal of Surgery
Published
2026-11-09
DOI
https://doi.org/10.1111/ans.71058
Primary Topic
Reconstructive Surgery and Microvascular Techniques
Type
article
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article

Relationship Between Post‐Operative Complications and Length of Stay in Patients Requiring Free Flap Reconstruction of the Head and Neck

James Wykes, Carsten Erich Palme, Masako Dunn, Leonard Lee et al.
ANZ Journal of Surgery
Reconstructive Surgery and Microvascular Techniques
article

Relationship Between Post‐Operative Complications and Length of Stay in Patients Requiring Free Flap Reconstruction of the Head and Neck

James Wykes, Carsten Erich Palme, Masako Dunn, Leonard Lee, Tsu-Hui Hubert Low, Timothy G. H. Manzie, Jonathan Robert Clark
article en

Abstract

BACKGROUND: Reconstructive with free flap procedures are often required following ablative removal of pathologies from the head and neck. The Clavien-Dindo Classification (CDC) system is widely used to grade complication severity; however, there are limited studies examining the relationship between complications and length of stay (LOS) in this cohort. PURPOSE: To evaluate the association between complication severity and both hospital and intensive care unit (ICU) LOS in patients undergoing head and neck free flap reconstruction. METHODS: This retrospective cohort study included 994 patients treated between 2016 and 2024. Complications were graded using the CDC system. LOS was analysed using generalised linear models with a Gamma distribution and log-link. Kruskal-Wallis tests were used for supplementary analysis. RESULTS: Complications occurred in 54.5% of patients. Higher CDC grades were significantly associated with longer ICU (p < 0.001) and hospital LOS (p < 0.001). CDC Grades II, IIIb and IVa were independently associated with prolonged ICU LOS. All CDC grades were associated with increased hospital LOS. CONCLUSION: This study provides outcome data linking complication severity to ICU and hospital LOS. The CDC, while advantageous, fails to separate significant negative outcomes, such as free flap failure from a more simple return to theatre. Modifications may further improve distinction in complications and effect on overall hospital stay.

ANZ Journal of Surgery
Griffith University (AU), Bond University (AU), The University of Sydney (AU), Royal Prince Alfred Hospital (AU), Chris O’Brien Lifehouse (AU), Sydney Local Health District (AU), National Health and Medical Research Council (AU), Macquarie University (AU)
Reconstructive Surgery and Microvascular Techniques
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