Cyanation of Dihydropyrrolo[2,1‐ a ]isoquinoline With Phenylacetonitrile
An efficient cyanation reaction for the direct cyanation of dihydropyrrolo[2,1‐ a ]isoquinoline with phenylacetonitrile has been described. This reaction is performed in DMF using CuI as the promoter. Various substrates are well compatible, affording the corresponding products in moderate‐to‐good yields. This work provides an operationally simple approach to the construction of Lamellarin scaffolds.
Authors
- D. Chen
- Chao Liu (ORCID: https://orcid.org/0000-0002-5482-4940)
- 沈悦海
- Jian Li (ORCID: https://orcid.org/0000-0001-6713-1302)
- Shuo Yuan (ORCID: https://orcid.org/0009-0001-0487-6937)
- Wei Lv
- Zhikang Lv
Institutions
- Kunming University of Science and Technology (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2026-11-09
- DOI
- https://doi.org/10.1002/ejoc.70967
- Primary Topic
- Advanced Synthetic Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00