Pseudotumeurs orbito-palpébrales révélatrices d'une maladie de Rosai-Dorfman-Destombes : à propos d'un cas au service de médecine interne de l'Hôpital Abass Ndao de Dakar

Introduction: Rosai-Dorfman-Destombes disease (RDD) is a rare histiocytosis with highly variable clinical presentations. Case presentation: We report the case of a young woman with bilateral orbito-palpebral pseudotumours and bilateral parotid enlargement, slowly progressing over eight years. The diagnosis was confirmed by histopathology, which showed large, foamy histiocytes with emperipolesis, positive for S100 and negative for CD1a on immunohistochemistry. Corticosteroid therapy led to marked clinical improvement within three months. Conclusion: This case underscores the importance of vigilance when facing any unusual orbito-palpebral or parotid pseudotumoral mass.