Association of DASH and Mediterranean Diet Adherence with Phase Angle in Patients with Crohn’s Disease: An Exploratory Cross-Sectional Study

Background/Objectives: Patients with Crohn’s disease (CD) are at increased risk of malnutrition, which may be reflected by reduced phase angle (PhA), a bioelectrical impedance marker of cellular integrity. This exploratory study investigated associations between Mediterranean and DASH diet adherence and PhA in adults with CD. Methods: This cross-sectional study included 39 adults with CD, mostly in clinical remission, from a Greek public hospital. PhA was measured by bioelectrical impedance analysis, and dietary quality was assessed with the MedDietScore and an adapted DASH score; the primary exposure was a food-based DASH index (seven food-group components), and the full 10-component score was exploratory. Associations were examined with multiple linear regression models adjusted for sex and physical activity. Results: After adjustment for sex and physical activity, each one-point higher food-based DASH index was associated with a 0.29° higher PhA, with a 95% CI from −0.003 to 0.588 (n = 35). In exploratory analyses, the full score, which includes qualitatively scored nutrient components, was also positively associated with PhA (B = 0.230, 95% CI 0.042–0.418). No clear association was observed for the total MedDietScore or full-fat dairy consumption. Conclusions: In adults with CD, the adjusted estimate for DASH-type food choices and PhA was positive but imprecise. These hypothesis-generating findings require confirmation in longitudinal and interventional studies.

Authors

Institutions

Publication Details

Journal
Diseases
Published
2026-11-08
DOI
https://doi.org/10.3390/diseases14110408
Primary Topic
Nutritional Studies and Diet
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
NOV
article

Association of DASH and Mediterranean Diet Adherence with Phase Angle in Patients with Crohn’s Disease: An Exploratory Cross-Sectional Study

Sousana Κ. Papadopoulou, Konstantinos Soufleris, Constantinos Giaginis, Gavriela Voulgaridou et al.
Diseases
Nutritional Studies and Diet
article

Association of DASH and Mediterranean Diet Adherence with Phase Angle in Patients with Crohn’s Disease: An Exploratory Cross-Sectional Study

Sousana Κ. Papadopoulou, Konstantinos Soufleris, Constantinos Giaginis, Gavriela Voulgaridou, Paraskevi Detopoulou, Olga Magni, Konstantinos Papadimitriou, Evangelia Paplomata
article en

Abstract

Background/Objectives: Patients with Crohn’s disease (CD) are at increased risk of malnutrition, which may be reflected by reduced phase angle (PhA), a bioelectrical impedance marker of cellular integrity. This exploratory study investigated associations between Mediterranean and DASH diet adherence and PhA in adults with CD. Methods: This cross-sectional study included 39 adults with CD, mostly in clinical remission, from a Greek public hospital. PhA was measured by bioelectrical impedance analysis, and dietary quality was assessed with the MedDietScore and an adapted DASH score; the primary exposure was a food-based DASH index (seven food-group components), and the full 10-component score was exploratory. Associations were examined with multiple linear regression models adjusted for sex and physical activity. Results: After adjustment for sex and physical activity, each one-point higher food-based DASH index was associated with a 0.29° higher PhA, with a 95% CI from −0.003 to 0.588 (n = 35). In exploratory analyses, the full score, which includes qualitatively scored nutrient components, was also positively associated with PhA (B = 0.230, 95% CI 0.042–0.418). No clear association was observed for the total MedDietScore or full-fat dairy consumption. Conclusions: In adults with CD, the adjusted estimate for DASH-type food choices and PhA was positive but imprecise. These hypothesis-generating findings require confirmation in longitudinal and interventional studies.

DiseasesVol. 14(11)
University of Peloponnese (GR), International Hellenic University (GR), Aristotle University of Thessaloniki (GR), Theageneio General Hospital (GR), University of the Aegean (GR)
Nutritional Studies and Diet
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon