THE ROLE OF IRON DURING PREGNANCY AND ITS IMPACT ON THE FETUS AND THE MATERNAL ORGANISM

Pregnancy places unusually heavy demands on a woman's iron supply, driven by expanded red-cell production, the build-out of the fetoplacental unit, and the sheer growth of the fetus itself. The body responds to this in two directions at once: gut absorption and mobilisation of stored iron both ramp up adaptively, yet for most women this is not enough — without preventive measures, some degree of iron-deficient state develops in almost everyone by the third trimester simply because reserves cannot keep pace with demand. This paper works through the physiology behind iron handling in pregnancy, how iron actually crosses the placenta, what happens to mother and fetus when iron runs short or, conversely, runs too high, and how iron status is currently monitored and adjusted across the trimesters. A recurring theme is the evidence for a U-shaped risk curve — obstetric and metabolic complications cluster at both ends of the iron spectrum, not just at the low end — which argues for tailoring iron supplementation to the individual rather than dosing everyone the same way.

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Publication Details

Journal
Central Asian Journal of Academic Research
Published
2026-11-09
DOI
https://doi.org/10.70413/cajar-v04-i10-a10161
Primary Topic
Iron Metabolism and Disorders
Type
article
Field-Weighted Citation Impact
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article

THE ROLE OF IRON DURING PREGNANCY AND ITS IMPACT ON THE FETUS AND THE MATERNAL ORGANISM

S. Z. Yuldasheva, S.N. Abdullaeva, F.R. Ikramova
Central Asian Journal of Academic Research
Iron Metabolism and Disorders
article

THE ROLE OF IRON DURING PREGNANCY AND ITS IMPACT ON THE FETUS AND THE MATERNAL ORGANISM

S. Z. Yuldasheva, S.N. Abdullaeva, F.R. Ikramova
article en

Abstract

Pregnancy places unusually heavy demands on a woman's iron supply, driven by expanded red-cell production, the build-out of the fetoplacental unit, and the sheer growth of the fetus itself. The body responds to this in two directions at once: gut absorption and mobilisation of stored iron both ramp up adaptively, yet for most women this is not enough — without preventive measures, some degree of iron-deficient state develops in almost everyone by the third trimester simply because reserves cannot keep pace with demand. This paper works through the physiology behind iron handling in pregnancy, how iron actually crosses the placenta, what happens to mother and fetus when iron runs short or, conversely, runs too high, and how iron status is currently monitored and adjusted across the trimesters. A recurring theme is the evidence for a U-shaped risk curve — obstetric and metabolic complications cluster at both ends of the iron spectrum, not just at the low end — which argues for tailoring iron supplementation to the individual rather than dosing everyone the same way.

Central Asian Journal of Academic ResearchVol. 4(10)
Tashkent State Medical University (UZ)
Iron Metabolism and Disorders
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