Antimicrobial activity of silver nanoparticle-incorporated polyphosphodiester coatings on titanium surfaces

Abstract Surface modification is widely applied in various fields, including medical engineering. In this study we develop polyphosphodiesters conjugated with a silver nanocomposites coating on titanium surfaces to impart an antibacterial function. Under optimized preparation conditions, we found that coated surfaces significantly reduced the number of viable bacteria and exhibited potent bactericidal activity against attached Escherichia coli (E. coli). These results suggest a viable practical strategy for creating antibacterial titanium surfaces.