Engineering yeast for anticancer drug biosynthesis
In a recently published Science article, S hen et al. established a modular yeast platform for the de novo biosynthesis of a direct precursor of etoposide and teniposide from glucose. This advance provides unprecedented perspectives for a sustainable supply chain for these important anticancer drugs.
Authors
- Nicolas Gautron (ORCID: https://orcid.org/0000-0002-2184-7302)
- Vincent Courdavault (ORCID: https://orcid.org/0000-0001-8902-4532)
- Nicolas Papon (ORCID: https://orcid.org/0000-0001-6265-7321)
Institutions
- Université de Tours (FR)
- Biomolécules et Biotechnologies Végétales (FR)
- Université d'Angers (FR)
Publication Details
- Journal
- Cell Discovery
- Published
- 2026-11-09
- DOI
- https://doi.org/10.1038/s41421-026-00937-x
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00