Peak expectations: a question of power and timing
We thank Araneda and colleagues for their comments[1][1] on our trial of epinephrine and ropivacaine in bilateral transversus abdominis plane blocks.[2][2] We agree that a non-significant difference in maximum plasma concentration (Cmax) does not establish equivalence. Our comparison was too
Authors
- Alexandre Destère (ORCID: https://orcid.org/0000-0001-6147-9201)
- Axel Maurice-Szamburski (ORCID: https://orcid.org/0000-0003-4225-7392)
- Romain Rozier (ORCID: https://orcid.org/0009-0009-0294-8122)
Institutions
- Centre Hospitalier Universitaire de Nice (FR)
- Hôpital l'Archet (FR)
- Hôpital Pasteur (FR)
Publication Details
- Journal
- Regional Anesthesia & Pain Medicine
- Published
- 2026-11-09
- DOI
- https://doi.org/10.1136/rapm-2026-108743
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00