Neuromorphic Training of VO 2 Device at Behavioral Timescale Inspired by the Plasticity of CA1 Neurons of Live Mouse Brain

ABSTRACT Realizing biologically relevant plasticity rules in hardware is a central goal in neuromorphic computing. This work demonstrates that an individual vanadium dioxide device exhibits features analogous to behavioral timescale synaptic plasticity observed in CA1 neurons of freely moving mice. By positioning the device close to the phase‐transition boundary, the history‐dependent dynamics of these VO 2 devices were leveraged to induce long‐lasting, pulse‐driven changes in conductance. A direct comparison with whole‐cell recordings from CA1 neurons in freely moving mice reveals that VO 2 channels exhibit plasticity‐like state changes after a strong input, suggesting an analog to plasticity induction in the brain. These results highlight VO 2 as a material platform capable of reproducing key temporal features of biologically relevant plasticity, suggesting a path toward neuromorphic hardware that more faithfully mirrors the adaptive capabilities of neural circuits in mammalian brains.