Self-reported bleeding patterns during extended etonogestrel implant use beyond 3 years

OBJECTIVE: To describe self-reported bleeding patterns among etonogestrel implant users beyond 3 years of use and assess perceived changes compared withthe first 3 years. METHODS: We conducted a cross-sectional study at University State of Campinas, Brazil, among women who continued using the same etonogestrel implant beyond 3 years after insertion. Participants completed a structured questionnaire assessing their usual bleeding characteristics during extended use, including bleeding/spotting episodes per month, bleeding/spotting days per month, and bleeding flow. They also reported perceived changes in these characteristics compared with the first 3 years of use. RESULTS: ) was 26.6 (IQR 23.8-30.1). The median duration of implant use was 3.9 years (IQR 3.40-5.08). Amenorrhoea was reported by 24.2%, and the median number of bleeding/spotting episodes and days per month was 1 (IQR 0-2) and 4 (IQR 0-7), respectively. Compared with the first 3 years, 62.7% reported unchanged or fewer bleeding episodes, 62.1% reported unchanged or fewer bleeding days, and 58.8% reported unchanged or reduced bleeding flow. CONCLUSION: Among women who continuied etonogestrel implant use beyond 3 years, approximately one-quarter reported amenorrhoea, and most perceived no increase in bleeding frequency, duration, or flow compared with the first 3 years. However, these findings should be interpreted with caution because of the retrospective assessment and potential selection bias.

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Publication Details

Journal
The European Journal of Contraception & Reproductive Health Care
Published
2026-11-09
DOI
https://doi.org/10.1080/13625187.2026.2760253
Primary Topic
Reproductive Health and Contraception
Type
article
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article

Self-reported bleeding patterns during extended etonogestrel implant use beyond 3 years

Cássia Raquel Teatin Juliato, Paula da Cunha Pereira, Luis Guillermo Bahamondes, Juliana de Toledo Piza Soares et al.
The European Journal of Contraception & Reproductive Health Care
Reproductive Health and Contraception
article

Self-reported bleeding patterns during extended etonogestrel implant use beyond 3 years

Cássia Raquel Teatin Juliato, Paula da Cunha Pereira, Luis Guillermo Bahamondes, Juliana de Toledo Piza Soares, Mariana R. B. Rossi-Elias, Ana C.H Marcelino
article en

Abstract

OBJECTIVE: To describe self-reported bleeding patterns among etonogestrel implant users beyond 3 years of use and assess perceived changes compared withthe first 3 years. METHODS: We conducted a cross-sectional study at University State of Campinas, Brazil, among women who continued using the same etonogestrel implant beyond 3 years after insertion. Participants completed a structured questionnaire assessing their usual bleeding characteristics during extended use, including bleeding/spotting episodes per month, bleeding/spotting days per month, and bleeding flow. They also reported perceived changes in these characteristics compared with the first 3 years of use. RESULTS: ) was 26.6 (IQR 23.8-30.1). The median duration of implant use was 3.9 years (IQR 3.40-5.08). Amenorrhoea was reported by 24.2%, and the median number of bleeding/spotting episodes and days per month was 1 (IQR 0-2) and 4 (IQR 0-7), respectively. Compared with the first 3 years, 62.7% reported unchanged or fewer bleeding episodes, 62.1% reported unchanged or fewer bleeding days, and 58.8% reported unchanged or reduced bleeding flow. CONCLUSION: Among women who continuied etonogestrel implant use beyond 3 years, approximately one-quarter reported amenorrhoea, and most perceived no increase in bleeding frequency, duration, or flow compared with the first 3 years. However, these findings should be interpreted with caution because of the retrospective assessment and potential selection bias.

The European Journal of Contraception & Reproductive Health Care
Universidade Estadual de Campinas (UNICAMP) (BR)
Reproductive Health and Contraception
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Self-reported bleeding patterns during extended etonogestrel implant use beyond 3 years — Cássia Raquel Teatin Juliato, Paula da Cunha Pereira, et al. · The European Journal of Contraception & Reproductive Health Care (2026) | TGRS Research Map | TGRS