Intrathyroidal Parathyroid Adenoma Mimicking a Thyroid Nodule on Ultrasound

We report the 18 F-Choline PET/CT findings of an intrathyroidal parathyroid adenoma (IPA) in a 30-year-old woman with primary hyperparathyroidism. Cervical ultrasound showed no parathyroid abnormality but revealed a hypoechoic nodule within the left thyroid lobe, initially misdiagnosed as a thyroid nodule. 18 F-Choline PET/CT demonstrated intense focal uptake in the lesion, precisely localized to the intrathyroidal region. Postoperative pathology confirmed an IPA. This case highlights the value of 18 F-Choline PET/CT in accurately localizing an IPA misdiagnosed as a thyroid nodule on ultrasound, thereby avoiding unnecessary fine-needle aspiration and thyroid surgery.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2026-11-09
DOI
https://doi.org/10.1097/rlu.0000000000006740
Primary Topic
Thyroid and Parathyroid Surgery
Type
article
Field-Weighted Citation Impact
0.00
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article

Intrathyroidal Parathyroid Adenoma Mimicking a Thyroid Nodule on Ultrasound

Yan Wan, Lijuan Feng, Wenbo Feng, Hao Wang
Clinical Nuclear Medicine
Thyroid and Parathyroid Surgery
article

Intrathyroidal Parathyroid Adenoma Mimicking a Thyroid Nodule on Ultrasound

Yan Wan, Lijuan Feng, Wenbo Feng, Hao Wang
article en

Abstract

We report the 18 F-Choline PET/CT findings of an intrathyroidal parathyroid adenoma (IPA) in a 30-year-old woman with primary hyperparathyroidism. Cervical ultrasound showed no parathyroid abnormality but revealed a hypoechoic nodule within the left thyroid lobe, initially misdiagnosed as a thyroid nodule. 18 F-Choline PET/CT demonstrated intense focal uptake in the lesion, precisely localized to the intrathyroidal region. Postoperative pathology confirmed an IPA. This case highlights the value of 18 F-Choline PET/CT in accurately localizing an IPA misdiagnosed as a thyroid nodule on ultrasound, thereby avoiding unnecessary fine-needle aspiration and thyroid surgery.

Clinical Nuclear Medicine
University of Electronic Science and Technology of China (CN), Jiujiang First People's Hospital (CN)
Thyroid and Parathyroid Surgery
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