AustrAIHANZ – consensus guidelines on the investigation and management of autoimmune haemolytic anaemia in Australia and New Zealand

Autoimmune haemolytic anaemia is a rare immune-mediated disorder leading to accelerated red cell destruction and anaemia. There is considerable clinical heterogeneity, with some patients barely requiring intervention, while others experience fulminant haemolysis and experience mortality rates as high as 30% with severe anaemia and end-organ ischaemia. As there is insufficient high-quality clinical data to guide management, we developed consensus practice statements based on Delphi methodology to provide clinicians with guidelines to approach diagnostic investigations, initiation of therapy, second-line treatment options, supportive care and pregnant patients.

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Publication Details

Journal
Internal Medicine Journal
Published
2026-11-08
DOI
https://doi.org/10.1111/imj.70656
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
0.00

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article

AustrAIHANZ – consensus guidelines on the investigation and management of autoimmune haemolytic anaemia in Australia and New Zealand

Philip Choi, Eileen Merriman, Ashwini Bennett, Anoop Kumar Enjeti et al.
Internal Medicine Journal
Blood groups and transfusion
article

AustrAIHANZ – consensus guidelines on the investigation and management of autoimmune haemolytic anaemia in Australia and New Zealand

Philip Choi, Eileen Merriman, Ashwini Bennett, Anoop Kumar Enjeti, Jun Yen Ng, Danny Chung Hsu, Anastazia Keegan, Robert J Bird, Isaac Goncalves, Chee Wee Tan
article en

Abstract

Autoimmune haemolytic anaemia is a rare immune-mediated disorder leading to accelerated red cell destruction and anaemia. There is considerable clinical heterogeneity, with some patients barely requiring intervention, while others experience fulminant haemolysis and experience mortality rates as high as 30% with severe anaemia and end-organ ischaemia. As there is insufficient high-quality clinical data to guide management, we developed consensus practice statements based on Delphi methodology to provide clinicians with guidelines to approach diagnostic investigations, initiation of therapy, second-line treatment options, supportive care and pregnant patients.

Internal Medicine Journal
South Australia Pathology (AU), Australian National University (AU), Royal Adelaide Hospital (AU), The Royal Melbourne Hospital (AU), University of Auckland (NZ), Peter MacCallum Cancer Centre (AU), Liverpool Hospital (AU), King Edward Memorial Hospital (AU), Princess Alexandra Hospital (AU), North Shore Hospital (NZ), Canberra Hospital (AU), UNSW Sydney (AU), Monash Health (AU), Calvary Mater Newcastle Hospital (AU), Pathwest Laboratory Medicine (AU), ACT Government (AU), Central Adelaide Local Health Network (AU), NSW Health Pathology (AU), Monash University (AU), University of Newcastle Australia (AU)
Sanofi, Swedish Orphan Biovitrum
Good health and well-being
Blood groups and transfusion
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