In cases of upper gastrointestinal bleeding, when should IV omeprazole be administered as an infusion rather than a bolus?

The decision to use IV omeprazole as an infusion rather than a bolus in upper gastrointestinal bleeding is primarily guided by individual risk assessment and post-endoscopic context, with infusions often recommended for high-risk rebleeding post-endoscopy. Limited evidence directly compares the routes before endoscopic confirmation.